Polyglyceryl-10 Hydroxypropyl Ethylhexyl Ether

INCI: POLYGLYCERYL-10 HYDROXYPROPYL ETHYLHEXYL ETHER

CAS Number
Not readily available
Function
Emulsifying; solubilizing; conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not covered by CIR polyglyceryl fatty acid ester assessment โ€” this is an ether, not an ester; no independent CIR monograph identified

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Ether bond structure is not hydrolyzable by skin esterases, creating a different metabolic fate from polyglyceryl esters; potential 1,4-dioxane residual from propoxylation must be tested and controlled below 10 ppm per SCCS recommendation; safety assessment requires justification via read-across or supplier toxicological dossier.

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Concern Level: High

Frequently Asked Questions

Is Polyglyceryl-10 Hydroxypropyl Ethylhexyl Ether safe in cosmetics?

Ether bond structure is not hydrolyzable by skin esterases, creating a different metabolic fate from polyglyceryl esters; potential 1,4-dioxane residual from propoxylation must be tested and controlled below 10 ppm per SCCS recommendation; safety assessment requires justification via read-across or supplier toxicological dossier. The EU classifies Polyglyceryl-10 Hydroxypropyl Ethylhexyl Ether as "permitted". Safety rating: MODERATE.

Is Polyglyceryl-10 Hydroxypropyl Ethylhexyl Ether allowed in the EU?

Polyglyceryl-10 Hydroxypropyl Ethylhexyl Ether EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Polyglyceryl-10 Hydroxypropyl Ethylhexyl Ether do in cosmetics?

Polyglyceryl-10 Hydroxypropyl Ethylhexyl Ether functions as: Emulsifying; solubilizing; conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not readily available.

What is the Margin of Safety for Polyglyceryl-10 Hydroxypropyl Ethylhexyl Ether?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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