Is Polyglyceryl-2 Isostearate safe in cosmetics?
Polyglyceryl-2 Isostearate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Polyglyceryl-2 Isostearate
INCI: POLYGLYCERYL-2 ISOSTEARATE
Polyglyceryl-2 Isostearate (CAS 73296-86-3) is a cosmetic cosmetic ingredient functioning as Emulsifying, Skin Conditioning. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 73296-86-3 →
Auto-generated CPSR Part A draft with source citations
Function
Emulsifying, Skin Conditioning
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
3-(2,3-dihydroxypropoxy)propane-1,2-diol;16-methylheptadecanoic acid
InChIKey
CKIYSWRVDRLJDR-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
CIR panel assessed polyglyceryl fatty acid esters as safe as used in cosmetics (2023)
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Polyglyceryl-2 Isostearate.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
1 property record from structured ingredient metadata.
emulsifier
{"cas_number": "Various_2_Iso", "ingredient_class": "O/W_emulsifier", "chemical_type": "polyglycerol_ester", "HLB_value": "12.5", "HLB_required_for_oil_phase": "10-14", "emulsion_type_primary": "O/W", "droplet_size_typical_um": "0.5-2", "surface_tension_reduction_mN_m": "32", "interfacial_tension_reduction": "36", "foam_formation": "moderate", "foam_stability": "moderate", "liquid_crystal_formatio…
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Emulsifier
Softener and conditioner
Surfactant (surface active agent)
Expert Verdict
Expert safety assessment and concern-level summary for Polyglyceryl-2 Isostearate.
Regulatory Flags
emulsifier
natural-derived
cosmos-compatible
Chemical Function
Emulsifier
Softener and conditioner
Surfactant (surface active agent)
Regulatory Lists
Canada; Personal care; Substances in PCP - Canada (4/2014)
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Polyglyceryl-2 Isostearate allowed in the EU?
Polyglyceryl-2 Isostearate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Polyglyceryl-2 Isostearate do in cosmetics?
Polyglyceryl-2 Isostearate functions as: Emulsifying, Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 73296-86-3.
Is Polyglyceryl-2 Isostearate used outside cosmetics?
Polyglyceryl-2 Isostearate also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Polyglyceryl-2 Isostearate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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