Ilex Paraguariensis Leaf Extract

INCI: ILEX PARAGUARIENSIS LEAF EXTRACT

CAS Number
73296-98-7
Function
Skin Conditioning, Antioxidant, Astringent, Hair Conditioning
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No FDA cosmetic-specific restrictions. Not evaluated by CIR. Not classified as GRASE sunscreen active. Recognized in FDA Substances Added to Food database (UNII 1Q953B4O4F). Safety governed by general FD&C Act adulteration and misbranding provisions.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Ilex Paraguariensis Leaf Extract (CAS 73296-98-7) is permitted in the EU under Regulation 1223/2009 and has no specific cosmetic restrictions in the US under the FD&C Act. Key concern is process-generated PAH contamination from smoke-drying; GMP-grade extracts with controlled PAH specifications materially reduce this risk.

โš ๏ธ
Concern Level: Low

Regulatory Flags

pah-contamination-risk no-sccs-opinion no-dermal-absorption-data no-hript-data caffeine-containing xanthine-bearing

Frequently Asked Questions

Is Ilex Paraguariensis Leaf Extract safe in cosmetics?

Ilex Paraguariensis Leaf Extract (CAS 73296-98-7) is permitted in the EU under Regulation 1223/2009 and has no specific cosmetic restrictions in the US under the FD&C Act. Key concern is process-generated PAH contamination from smoke-drying; GMP-grade extracts with controlled PAH specifications materially reduce this risk. The EU classifies Ilex Paraguariensis Leaf Extract as "permitted". Safety rating: GOOD.

Is Ilex Paraguariensis Leaf Extract allowed in the EU?

Ilex Paraguariensis Leaf Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Ilex Paraguariensis Leaf Extract do in cosmetics?

Ilex Paraguariensis Leaf Extract functions as: Skin Conditioning, Antioxidant, Astringent, Hair Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 73296-98-7.

What is the Margin of Safety for Ilex Paraguariensis Leaf Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

๐Ÿ“ฑ

Is Ilex Paraguariensis Leaf Extract in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Ilex Paraguariensis Leaf Extract in your formulation.