Polyglyceryl-25/Caprolactone

INCI: POLYGLYCERYL-25/CAPROLACTONE

CAS Number
Not assigned (copolymer)
Function
Buffering, film forming, hair conditioning, solvent, surfactant – cleansing, surfactant – emulsifying
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Not specifically CIR-reviewed (caprolactone copolymer — falls outside the polyglyceryl fatty acid ester monograph)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Data gap — no dedicated CIR/SCCS safety monograph; caprolactone moiety requires separate toxicological justification in CPSR; verify residual caprolactone monomer levels in CoA

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Concern Level: Moderate

Frequently Asked Questions

Is Polyglyceryl-25/Caprolactone safe in cosmetics?

Data gap — no dedicated CIR/SCCS safety monograph; caprolactone moiety requires separate toxicological justification in CPSR; verify residual caprolactone monomer levels in CoA The EU classifies Polyglyceryl-25/Caprolactone as "permitted". Safety rating: MODERATE.

Is Polyglyceryl-25/Caprolactone allowed in the EU?

Polyglyceryl-25/Caprolactone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Polyglyceryl-25/Caprolactone do in cosmetics?

Polyglyceryl-25/Caprolactone functions as: Buffering, film forming, hair conditioning, solvent, surfactant – cleansing, surfactant – emulsifying. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned (copolymer).

What is the Margin of Safety for Polyglyceryl-25/Caprolactone?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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