Polyglyceryl-3 Disiloxane Dimethicone

INCI: POLYGLYCERYL-3 DISILOXANE DIMETHICONE

CAS Number
Not assigned (siloxane polymer)
Function
Hair conditioning; skin conditioning; surfactant – emulsifying; surfactant – solubilizing; viscosity increasing (aqueous)
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Not restricted by FDA; no specific CIR monograph — assessed by read-across from dimethicone and polyglyceryl families

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Data gap — no dedicated toxicological dossier; safety relies entirely on structural read-across from dimethicone crosspolymers and polyglycerins

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Concern Level: Moderate

Frequently Asked Questions

Is Polyglyceryl-3 Disiloxane Dimethicone safe in cosmetics?

Data gap — no dedicated toxicological dossier; safety relies entirely on structural read-across from dimethicone crosspolymers and polyglycerins The EU classifies Polyglyceryl-3 Disiloxane Dimethicone as "permitted". Safety rating: MODERATE.

Is Polyglyceryl-3 Disiloxane Dimethicone allowed in the EU?

Polyglyceryl-3 Disiloxane Dimethicone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Polyglyceryl-3 Disiloxane Dimethicone do in cosmetics?

Polyglyceryl-3 Disiloxane Dimethicone functions as: Hair conditioning; skin conditioning; surfactant – emulsifying; surfactant – solubilizing; viscosity increasing (aqueous). It is classified as a cosmetic ingredient in our database. CAS number: Not assigned (siloxane polymer).

What is the Margin of Safety for Polyglyceryl-3 Disiloxane Dimethicone?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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