Polyglyceryl-4 Laurate/Sebacate

INCI: POLYGLYCERYL-4 LAURATE/SEBACATE

CAS Number
Not uniquely assigned (mixed ester of lauric + sebacic acid with polyglycerin-4)
Function
Surfactant – hydrotrope; surfactant – solubilizing agent
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Not restricted by FDA; CIR: safe as used (2023)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Hydrotrope function may increase penetration of other actives; formulate to be non-irritating.

⚠️
Concern Level: Low

Frequently Asked Questions

Is Polyglyceryl-4 Laurate/Sebacate safe in cosmetics?

Hydrotrope function may increase penetration of other actives; formulate to be non-irritating. The EU classifies Polyglyceryl-4 Laurate/Sebacate as "permitted". Safety rating: GOOD.

Is Polyglyceryl-4 Laurate/Sebacate allowed in the EU?

Polyglyceryl-4 Laurate/Sebacate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Polyglyceryl-4 Laurate/Sebacate do in cosmetics?

Polyglyceryl-4 Laurate/Sebacate functions as: Surfactant – hydrotrope; surfactant – solubilizing agent. It is classified as a cosmetic ingredient in our database. CAS number: Not uniquely assigned (mixed ester of lauric + sebacic acid with polyglycerin-4).

What is the Margin of Safety for Polyglyceryl-4 Laurate/Sebacate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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