Polyglyceryl-6 Pentastearate

INCI: POLYGLYCERYL-6 PENTASTEARATE

CAS Number
Not individually assigned (pentaester of stearic acid and hexaglycerol)
Function
W/O emulsifier; emollient
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes CIR-reviewed โ€” safe as used; VCRP use reported

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Formulate to be non-irritating; safety supported by CIR review and class read-across despite limited ingredient-specific toxicity studies.

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Concern Level: Low

Frequently Asked Questions

Is Polyglyceryl-6 Pentastearate safe in cosmetics?

Formulate to be non-irritating; safety supported by CIR review and class read-across despite limited ingredient-specific toxicity studies. The EU classifies Polyglyceryl-6 Pentastearate as "permitted". Safety rating: GOOD.

Is Polyglyceryl-6 Pentastearate allowed in the EU?

Polyglyceryl-6 Pentastearate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Polyglyceryl-6 Pentastearate do in cosmetics?

Polyglyceryl-6 Pentastearate functions as: W/O emulsifier; emollient. It is classified as a cosmetic ingredient in our database. CAS number: Not individually assigned (pentaester of stearic acid and hexaglycerol).

What is the Margin of Safety for Polyglyceryl-6 Pentastearate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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