Polyquaternium-76

INCI: POLYQUATERNIUM-76

CAS Number
Confidential (claimed exempt under Australian NICNAS notification)
Function
Hair conditioning agent in shampoos at concentrations up to 0.5%
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted for cosmetic use

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Quaternary ammonium groups present structural alerts for sensitization and corrosion, but risks are mitigated at low use concentrations and by anionic co-surfactants in formulations; aquatic toxicity noted (algae EbC50 = 0.649 mg/L).

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Concern Level: Low

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Polyquaternium-76 safe in cosmetics?

Quaternary ammonium groups present structural alerts for sensitization and corrosion, but risks are mitigated at low use concentrations and by anionic co-surfactants in formulations; aquatic toxicity noted (algae EbC50 = 0.649 mg/L). The EU classifies Polyquaternium-76 as "permitted". Safety rating: GOOD.

Is Polyquaternium-76 allowed in the EU?

Polyquaternium-76 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Polyquaternium-76 do in cosmetics?

Polyquaternium-76 functions as: Hair conditioning agent in shampoos at concentrations up to 0.5%. It is classified as a cosmetic ingredient in our database. CAS number: Confidential (claimed exempt under Australian NICNAS notification).

What is the Margin of Safety for Polyquaternium-76?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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