Moderate Cosmetic Ingredient NOAEL Data

Polyvinyl Acetate

CAS Number
9003-20-7
Function
Adhesion/cohesion promoter; Anti-static agent; Binder; Degradant/impurity; Dispersing agent; Emulsifier; Filler; Film former; Flavouring and nutrient; Hair fixative; Processing aids not otherwise specified; Stabilizing agent; Thickening agent
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes CIR: S - IJT 36(Suppl 2):14-58, 2017

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

2 study endpoints found for Polyvinyl Acetate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 25000 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB
NOAEL 25000 mg/kg bw/day oral mouse Short Term Toxicity COSMOS_DB

Expert Verdict

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Concern Level: Low

Regulatory Flags

fda_food_additive

Frequently Asked Questions

Is Polyvinyl Acetate safe in cosmetics?

Polyvinyl Acetate has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted. 2 toxicological study endpoint(s) are available in our database.

Is Polyvinyl Acetate allowed in the EU?

Polyvinyl Acetate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Polyvinyl Acetate do in cosmetics?

Polyvinyl Acetate functions as: Adhesion/cohesion promoter; Anti-static agent; Binder; Degradant/impurity; Dispersing agent; Emulsifier; Filler; Film former; Flavouring and nutrient; Hair fixative; Processing aids not otherwise specified; Stabilizing agent; Thickening agent. It is classified as a cosmetic ingredient in our database. CAS number: 9003-20-7.

What is the Margin of Safety for Polyvinyl Acetate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Polyvinyl Acetate?

The NOAEL (No Observed Adverse Effect Level) for Polyvinyl Acetate is 25000 mg/kg bw/day based on a Short Term Toxicity study via oral route in rat. A total of 2 study endpoints are available. Source: COSMOS_DB.

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