Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
10 study endpoints found for Potassium Acesulfame. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 750 mg/kg bw/day | oral | dog | Chronic | COSMOS_DB |
| NOAEL | 300 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
| NOAEL | 3000 mg/kg bw/day | oral | rat | Multigeneration Reproductive | COSMOS_DB |
| NOAEL | 3000 mg/kg bw/day | oral | rat | Reproductive-developmental | COSMOS_DB |
| NOAEL | 3000 mg/kg bw/day | oral | rat | Developmental | COSMOS_DB |
| NOAEL | 3000 mg/kg bw/day | oral | rat | Reproductive | COSMOS_DB |
| NOAEL | 900 mg/kg bw/day | oral | rabbit | Developmental | COSMOS_DB |
| NOAEL | 10000 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| NOAEL | 1500 mg/kg bw/day | oral | rat | Carcinogenicity | COSMOS_DB |
| NOAEL | 1500 mg/kg bw/day | oral | rat | Carcinogenicity | COSMOS_DB |
Expert Verdict
Minimal — primarily used in oral care products for sweetening/taste masking; environmental persistence concerns emerging in wastewater literature but not relevant to product safety; if marketing natural/clean claims, note this is a synthetic sweetener
Regulatory Flags
Frequently Asked Questions
Is Potassium Acesulfame safe in cosmetics?
Minimal — primarily used in oral care products for sweetening/taste masking; environmental persistence concerns emerging in wastewater literature but not relevant to product safety; if marketing natural/clean claims, note this is a synthetic sweetener The EU classifies Potassium Acesulfame as "permitted". Safety rating: EXCELLENT. 10 toxicological study endpoint(s) are available in our database.
Is Potassium Acesulfame allowed in the EU?
Potassium Acesulfame EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Potassium Acesulfame do in cosmetics?
Potassium Acesulfame functions as: Fragrance (taste-masking/sweetening agent in oral care contexts). It is classified as a cosmetic ingredient in our database. CAS number: 55589-62-3.
What is the Margin of Safety for Potassium Acesulfame?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Potassium Acesulfame?
The NOAEL (No Observed Adverse Effect Level) for Potassium Acesulfame is 750 mg/kg bw/day based on a Chronic study via oral route in dog. A total of 10 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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Related Ingredients
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