3-Methyl-5-Phenyl-2-Pentenenitrile (Citrontrile / Citronitrile)

INCI: TRANS-3-METHYL-5-PHENYL-2-PENTENENITRILE

CAS Number
93893-89-1 (mixture); Z-isomer: 53243-59-7; E-isomer: 53243-60-0
Function
Perfuming / Fragrance (citrus-fruity, balsamic note)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
EU Max Conc. variable by category
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not restricted by FDA

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Confirmed skin sensitizer with IFRA concentration restrictions varying by product category (e.g., 0.029% in hand cream, 0.0097% in baby products).

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Concern Level: Moderate

Regulatory Flags

potential-allergen fragrance-component

Frequently Asked Questions

Is 3-Methyl-5-Phenyl-2-Pentenenitrile (Citrontrile / Citronitrile) safe in cosmetics?

Confirmed skin sensitizer with IFRA concentration restrictions varying by product category (e.g., 0.029% in hand cream, 0.0097% in baby products). The EU classifies 3-Methyl-5-Phenyl-2-Pentenenitrile (Citrontrile / Citronitrile) as "restricted". Safety rating: MODERATE.

Is 3-Methyl-5-Phenyl-2-Pentenenitrile (Citrontrile / Citronitrile) allowed in the EU?

3-Methyl-5-Phenyl-2-Pentenenitrile (Citrontrile / Citronitrile) EU regulatory status: restricted. Maximum allowed concentration: variable by category. This is based on EU Regulation 1223/2009 and its amendments.

What does 3-Methyl-5-Phenyl-2-Pentenenitrile (Citrontrile / Citronitrile) do in cosmetics?

3-Methyl-5-Phenyl-2-Pentenenitrile (Citrontrile / Citronitrile) functions as: Perfuming / Fragrance (citrus-fruity, balsamic note). It is classified as a cosmetic ingredient in our database. CAS number: 93893-89-1 (mixture); Z-isomer: 53243-59-7; E-isomer: 53243-60-0.

What is the Margin of Safety for 3-Methyl-5-Phenyl-2-Pentenenitrile (Citrontrile / Citronitrile)?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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