Potassium Glycyrrhetinate

INCI: POTASSIUM GLYCYRRHETINATE

CAS Number
85985-61-1
Function
Skin conditioning agent, fragrance
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes CIR-reviewed as part of glycyrrhetinic acid group โ€” concluded safe as used in cosmetics

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

High oral doses of glycyrrhizic acid/glycyrrhetinic acid can cause pseudoaldosteronism (hypertension, hypokalemia); irrelevant at typical cosmetic dermal use levels. Confirm use concentration aligns with CIR-reviewed levels.

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Concern Level: Low

Regulatory Flags

fragrance-component

Frequently Asked Questions

Is Potassium Glycyrrhetinate safe in cosmetics?

High oral doses of glycyrrhizic acid/glycyrrhetinic acid can cause pseudoaldosteronism (hypertension, hypokalemia); irrelevant at typical cosmetic dermal use levels. Confirm use concentration aligns with CIR-reviewed levels. The EU classifies Potassium Glycyrrhetinate as "permitted". Safety rating: GOOD.

Is Potassium Glycyrrhetinate allowed in the EU?

Potassium Glycyrrhetinate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Potassium Glycyrrhetinate do in cosmetics?

Potassium Glycyrrhetinate functions as: Skin conditioning agent, fragrance. It is classified as a cosmetic ingredient in our database. CAS number: 85985-61-1.

What is the Margin of Safety for Potassium Glycyrrhetinate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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