Epoxyguaiene

INCI: EPOXYGUAIENE

CAS Number
68071-23-8 [^1_4][^1_7]
Function
Fragrance agent
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” no specific prohibition under 21 CFR

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Epoxide ring on a sesquiterpene skeleton raises QSAR alerts for sensitization and mutagenicity; IFRA may have usage restrictions; oxidation products may increase sensitization risk over shelf life; stability testing critical

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Concern Level: Moderate

Regulatory Flags

potential-allergen fragrance-component

Frequently Asked Questions

Is Epoxyguaiene safe in cosmetics?

Epoxide ring on a sesquiterpene skeleton raises QSAR alerts for sensitization and mutagenicity; IFRA may have usage restrictions; oxidation products may increase sensitization risk over shelf life; stability testing critical The EU classifies Epoxyguaiene as "permitted". Safety rating: MODERATE.

Is Epoxyguaiene allowed in the EU?

Epoxyguaiene EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Epoxyguaiene do in cosmetics?

Epoxyguaiene functions as: Fragrance agent. It is classified as a cosmetic ingredient in our database. CAS number: 68071-23-8 [^1_4][^1_7].

What is the Margin of Safety for Epoxyguaiene?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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