Potassium Thiocyanate
INCI: POTASSIUM THIOCYANATE
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
1 study endpoint found for Potassium Thiocyanate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 20 mg/kg bw/day | oral | rat | oral | REACH |
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Expert Verdict
Systemic toxicity concern — thiocyanate ion inhibits iodine uptake by the thyroid. Oral LD50 is relatively low. Anti-thyroid effects documented. Use at any significant concentration requires careful safety assessment.
Regulatory Flags
Frequently Asked Questions
Is Potassium Thiocyanate safe in cosmetics?
Systemic toxicity concern — thiocyanate ion inhibits iodine uptake by the thyroid. Oral LD50 is relatively low. Anti-thyroid effects documented. Use at any significant concentration requires careful safety assessment. The EU classifies Potassium Thiocyanate as "permitted". Safety rating: MODERATE. 1 toxicological study endpoint(s) are available in our database.
Is Potassium Thiocyanate allowed in the EU?
Potassium Thiocyanate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Potassium Thiocyanate do in cosmetics?
Potassium Thiocyanate functions as: Reducing agent; historically used in hair waving and straightening. It is classified as a cosmetic ingredient in our database. CAS number: 333-20-0.
What is the Margin of Safety for Potassium Thiocyanate?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Potassium Thiocyanate?
The NOAEL (No Observed Adverse Effect Level) for Potassium Thiocyanate is 20 mg/kg bw/day based on a oral study via oral route in rat. Source: REACH.
Compliance Tools
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Related Ingredients
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