PPG-12

CAS Number
25322-69-4 (polypropylene glycol, general)
Function
Humectant, skin conditioning, viscosity controlling agent, solvent
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Safe as used. CIR directly assessed PPGs โ‰ฅ3 as safe when formulated to be nonirritating.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Generally nontoxic and noncarcinogenic with no 1,4-dioxane risk; irritation concerns at higher concentrations mitigated through proper formulation.

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Concern Level: Low

Frequently Asked Questions

Is PPG-12 safe in cosmetics?

Generally nontoxic and noncarcinogenic with no 1,4-dioxane risk; irritation concerns at higher concentrations mitigated through proper formulation. The EU classifies PPG-12 as "permitted". Safety rating: GOOD.

Is PPG-12 allowed in the EU?

PPG-12 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does PPG-12 do in cosmetics?

PPG-12 functions as: Humectant, skin conditioning, viscosity controlling agent, solvent. It is classified as a cosmetic ingredient in our database. CAS number: 25322-69-4 (polypropylene glycol, general).

What is the Margin of Safety for PPG-12?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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