Propylene Glycol Oleate

INCI: PROPYLENE GLYCOL OLEATE

CAS Number
1330-80-9
Function
Skin conditioning – emollient; Surfactant – Emulsifying agent
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted; CIR "safe as used" (1999/2014); also permitted as direct/indirect food additive

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Mild erythema in rabbit irritation test at 1% (with and without lidocaine); confirmed penetration enhancer — exercise caution when co-formulating with potent actives

⚠️
Concern Level: Moderate

Frequently Asked Questions

Is Propylene Glycol Oleate safe in cosmetics?

Mild erythema in rabbit irritation test at 1% (with and without lidocaine); confirmed penetration enhancer — exercise caution when co-formulating with potent actives The EU classifies Propylene Glycol Oleate as "permitted". Safety rating: GOOD.

Is Propylene Glycol Oleate allowed in the EU?

Propylene Glycol Oleate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Propylene Glycol Oleate do in cosmetics?

Propylene Glycol Oleate functions as: Skin conditioning – emollient; Surfactant – Emulsifying agent. It is classified as a cosmetic ingredient in our database. CAS number: 1330-80-9.

What is the Margin of Safety for Propylene Glycol Oleate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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