Is Diisooctyl Adipate safe in cosmetics?
Diisooctyl Adipate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Diisooctyl Adipate
INCI: DIISOOCTYL ADIPATE
Diisooctyl Adipate (CAS 1330-86-5 (commercial mixture) / 108-63-4 (specific isomer: bis(6-methylheptyl) adipate)) is a cosmetic cosmetic ingredient functioning as Emollient, skin conditioning agent. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
Auto-generated CPSR Part A draft with source citations
CAS Number
1330-86-5 (commercial mixture) / 108-63-4 (specific isomer: bis(6-methylheptyl) adipate)
View industrial chemical safety profile →
Function
Emollient, skin conditioning agent
Safety Rating
GOOD
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — CIR assessed alkyl esters group as safe
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Diisooctyl Adipate.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for Diisooctyl Adipate.
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to Diisooctyl Adipate by CAS number or substance name.
Studies
18
Lowest NOAEL
178 mg/kg bw/day
Highest NOAEL
2187 mg/kg bw/day
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip
Frequently Asked Questions
Is Diisooctyl Adipate allowed in the EU?
Diisooctyl Adipate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Diisooctyl Adipate do in cosmetics?
Diisooctyl Adipate functions as: Emollient, skin conditioning agent. It is classified as a cosmetic ingredient in our database. CAS number: 1330-86-5 (commercial mixture) / 108-63-4 (specific isomer: bis(6-methylheptyl) adipate).
Compliance Tools
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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