NOAEL Studies Cosmetic Ingredient

Propylenediamine NOAEL Studies

INCI: PROPYLENEDIAMINE

CAS: 78-90-0 (1,2-diaminopropane)

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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ECHA 2 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ECHA NOAEL >=750 mg/kg bw/day rat oral: gavage - sub-chronic toxicity: oral dossier=ff205010-1753-40de-9db3-bc9c54f3782d.i6z; document=c1797ad3-22e3-4058-8493-d0cde2f3cf86_ff205010-1753-40de-9db3-bc9c54f3782d.i6d; document_key=c1797ad3-22e3-4058-8493-d0cde2f3cf86/ff205010-1753-40de-9db3-bc9c54f3782d; document_subtype=RepeatedDoseToxicityOral; literature=Name=Unnamed; ReferenceYear=2016; key_result=true; entry_uuid=d8041abc-37ba-4cc8-98d8-c4a21e671554
ECHA NOAEL 250 mg/kg bw/day rat oral: gavage - sub-chronic toxicity: oral dossier=ff205010-1753-40de-9db3-bc9c54f3782d.i6z; document=c1797ad3-22e3-4058-8493-d0cde2f3cf86_ff205010-1753-40de-9db3-bc9c54f3782d.i6d; document_key=c1797ad3-22e3-4058-8493-d0cde2f3cf86/ff205010-1753-40de-9db3-bc9c54f3782d; document_subtype=RepeatedDoseToxicityOral; literature=Name=Unnamed; ReferenceYear=2016; basis=clinical signs; key_result=true; entry_uuid=7b8d4177-b9db-4d92-879e-7ed395b1ea40