Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
⚠ GHS: H315 (skin irritant), H319 (eye irritant), H335 (respiratory irritant) . Air-sensitive — oxidation may form quinone intermediates that increase sensitization risk. Catechol structure is a known structural alert for skin sensitization.
Regulatory Flags
Frequently Asked Questions
Is Protocatechuicaldehyde safe in cosmetics?
⚠ GHS: H315 (skin irritant), H319 (eye irritant), H335 (respiratory irritant) . Air-sensitive — oxidation may form quinone intermediates that increase sensitization risk. Catechol structure is a known structural alert for skin sensitization. The EU classifies Protocatechuicaldehyde as "permitted". Safety rating: MODERATE.
Is Protocatechuicaldehyde allowed in the EU?
Protocatechuicaldehyde EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Protocatechuicaldehyde do in cosmetics?
Protocatechuicaldehyde functions as: Bleaching, antioxidant, skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 139-85-5.
What is the Margin of Safety for Protocatechuicaldehyde?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
Check Protocatechuicaldehyde compliance across multiple jurisdictions:
Related Ingredients
Is Protocatechuicaldehyde in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Protocatechuicaldehyde in your formulation.