Is Calcium Cyclamate safe in cosmetics?
Calcium Cyclamate has a safety rating of "POOR" in our database. EU status: prohibited. US status: prohibited.
Poor
Cosmetic Ingredient
Calcium Cyclamate
Also known as: Calcium bis(cyclohexylsulphamate), Calcium cyclohexane sulphamate, Calcium cyclohexanesulfamate, Calcium cyclohexylsulfamate (1:2), Calcium cyclohexylsulphamate (+6 more)
INCI: CALCIUM CYCLAMATE
Calcium Cyclamate (CAS 139-06-0) is a cosmetic cosmetic ingredient functioning as Flavouring (oral care sweetener). EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
View industrial chemical safety profile for CAS 139-06-0 →
Auto-generated CPSR Part A draft with source citations
Function
Flavouring (oral care sweetener)
Safety Rating
POOR
Regulatory Status
EU EU Status
prohibited
US US Status
prohibited
US Notes
Unfavorable — Historical NOAEL data from animal studies yields low MoS at anticipated oral care exposure
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Calcium Cyclamate.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Deodorizer
Expert Verdict
Expert safety assessment and concern-level summary for Calcium Cyclamate.
Known Synonyms
Calcium bis(cyclohexylsulphamate)
Calcium cyclohexane sulphamate
Calcium cyclohexanesulfamate
Calcium cyclohexylsulfamate (1:2)
Calcium cyclohexylsulphamate
Cyclamate, calcium salt
EINECS 205-349-4
Sucaryl calcium
Kalziumzyklamate
Calcium cyclamate(1:2)
UNII-X12LMJ1WYL
Chemical Function
Deodorizer
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
CYCLAMATE CALCIUM
ChEMBL ID
CHEMBL2104112
Max Phase
-1
Frequently Asked Questions
Is Calcium Cyclamate allowed in the EU?
Calcium Cyclamate EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Calcium Cyclamate do in cosmetics?
Calcium Cyclamate functions as: Flavouring (oral care sweetener). It is classified as a cosmetic ingredient in our database. CAS number: 139-06-0.
Is Calcium Cyclamate used outside cosmetics?
Calcium Cyclamate also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Calcium Cyclamate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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