Pyridoxine Tris-Hexyldecanoate

INCI: PYRIDOXINE TRIS-HEXYLDECANOATE [^1_16]

CAS Number
564478-51-9 [^1_14][^1_15]
Function
Humectant, skin conditioning; promotes filaggrin synthesis and NMF production; oil-soluble Vitamin B6 derivative [^1_14]
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted in cosmetics; no specific FDA monograph [^1_14]

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
high
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Relatively new ingredient (post-2000); limited independent published toxicology. Rely on supplier-provided safety dossier. Excellent heat and oxidation stability is a formulation advantage [^1_14]

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Concern Level: Moderate

Frequently Asked Questions

Is Pyridoxine Tris-Hexyldecanoate safe in cosmetics?

Relatively new ingredient (post-2000); limited independent published toxicology. Rely on supplier-provided safety dossier. Excellent heat and oxidation stability is a formulation advantage [^1_14] The EU classifies Pyridoxine Tris-Hexyldecanoate as "permitted". Safety rating: GOOD.

Is Pyridoxine Tris-Hexyldecanoate allowed in the EU?

Pyridoxine Tris-Hexyldecanoate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Pyridoxine Tris-Hexyldecanoate do in cosmetics?

Pyridoxine Tris-Hexyldecanoate functions as: Humectant, skin conditioning; promotes filaggrin synthesis and NMF production; oil-soluble Vitamin B6 derivative [^1_14]. It is classified as a cosmetic ingredient in our database. CAS number: 564478-51-9 [^1_14][^1_15].

What is the Margin of Safety for Pyridoxine Tris-Hexyldecanoate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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