Pyrrolidinyl Diaminopyrimidine Oxide

INCI: PYRROLIDINYL DIAMINOPYRIMIDINE OXIDE

CAS Number
55921-65-8
Function
Hair conditioning, Hair waving/straightening; marketed as anti-hair loss and hair growth promoter (kopyrrol/aminopyrimidine derivative)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not specifically regulated; permitted under general cosmetic ingredient provisions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Contains amine oxide functionality โ€” verify stability and potential N-nitrosamine formation under specific conditions. Primarily a hair care active; if formulating for skin, separate safety justification needed. No CIR review โ€” rely on supplier dossier

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Concern Level: Moderate

Frequently Asked Questions

Is Pyrrolidinyl Diaminopyrimidine Oxide safe in cosmetics?

Contains amine oxide functionality โ€” verify stability and potential N-nitrosamine formation under specific conditions. Primarily a hair care active; if formulating for skin, separate safety justification needed. No CIR review โ€” rely on supplier dossier The EU classifies Pyrrolidinyl Diaminopyrimidine Oxide as "permitted". Safety rating: MODERATE.

Is Pyrrolidinyl Diaminopyrimidine Oxide allowed in the EU?

Pyrrolidinyl Diaminopyrimidine Oxide EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Pyrrolidinyl Diaminopyrimidine Oxide do in cosmetics?

Pyrrolidinyl Diaminopyrimidine Oxide functions as: Hair conditioning, Hair waving/straightening; marketed as anti-hair loss and hair growth promoter (kopyrrol/aminopyrimidine derivative). It is classified as a cosmetic ingredient in our database. CAS number: 55921-65-8.

What is the Margin of Safety for Pyrrolidinyl Diaminopyrimidine Oxide?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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