Pyrus Malus Leaf Extract

INCI: PYRUS MALUS (APPLE) LEAF EXTRACT

CAS Number
85251-63-4 / EINECS 286-475-7
Function
Skin Conditioning, Antioxidant
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No VCRP reported uses at time of CIR review; CIR: Safe (2016)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Volatile oil from fresh leaves contains eucalyptol (43.7%), classified as cytotoxic to cancer cell lines *in vitro* โ€” ensure extraction method does not concentrate this fraction; phloridzin has skin-bleaching potential (drug claim, not cosmetic)

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Concern Level: Moderate

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Pyrus Malus Leaf Extract safe in cosmetics?

Volatile oil from fresh leaves contains eucalyptol (43.7%), classified as cytotoxic to cancer cell lines *in vitro* โ€” ensure extraction method does not concentrate this fraction; phloridzin has skin-bleaching potential (drug claim, not cosmetic) The EU classifies Pyrus Malus Leaf Extract as "permitted". Safety rating: GOOD.

Is Pyrus Malus Leaf Extract allowed in the EU?

Pyrus Malus Leaf Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Pyrus Malus Leaf Extract do in cosmetics?

Pyrus Malus Leaf Extract functions as: Skin Conditioning, Antioxidant. It is classified as a cosmetic ingredient in our database. CAS number: 85251-63-4 / EINECS 286-475-7.

What is the Margin of Safety for Pyrus Malus Leaf Extract?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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