Alkanna Tinctoria Root Extract

INCI: ALKANNA TINCTORIA ROOT EXTRACT

CAS Number
85251-58-7 / 23444-65-7 / 517-88-4
Function
Skin Conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not restricted; no CIR review; FDA has not issued specific guidance

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Pyrrolizidine alkaloids (PAs) present in this Boraginaceae plant extract; 1,2-unsaturated PAs are hepatotoxic, genotoxic, and carcinogenic. PA content must be tested. Contains naphthoquinones that can stain skin and may cause irritation.

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Concern Level: High

Regulatory Flags

plant-extract natural-origin

Frequently Asked Questions

Is Alkanna Tinctoria Root Extract safe in cosmetics?

Pyrrolizidine alkaloids (PAs) present in this Boraginaceae plant extract; 1,2-unsaturated PAs are hepatotoxic, genotoxic, and carcinogenic. PA content must be tested. Contains naphthoquinones that can stain skin and may cause irritation. The EU classifies Alkanna Tinctoria Root Extract as "permitted". Safety rating: MODERATE.

Is Alkanna Tinctoria Root Extract allowed in the EU?

Alkanna Tinctoria Root Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Alkanna Tinctoria Root Extract do in cosmetics?

Alkanna Tinctoria Root Extract functions as: Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 85251-58-7 / 23444-65-7 / 517-88-4.

What is the Margin of Safety for Alkanna Tinctoria Root Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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