Moderate Cosmetic Ingredient

r-(Aspartyl Oligopeptide-162 Aspartyl rh-Polypeptide-48)

INCI: R-(ASPARTYL OLIGOPEPTIDE-162 ASPARTYL RH-POLYPEPTIDE-48)

CAS Number
Not assigned
Function
Skin conditioning (recombinant fusion peptide; anti-ageing biotech active)
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted for cosmetic use; manufacturer must substantiate safety

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Same concerns as \#7; CHO cell origin; limited safety dossier; regulatory status ambiguous in the EU — mandatory verification with current CosIng before use

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Concern Level: Moderate

Frequently Asked Questions

Is r-(Aspartyl Oligopeptide-162 Aspartyl rh-Polypeptide-48) safe in cosmetics?

Same concerns as \#7; CHO cell origin; limited safety dossier; regulatory status ambiguous in the EU — mandatory verification with current CosIng before use The EU classifies r-(Aspartyl Oligopeptide-162 Aspartyl rh-Polypeptide-48) as "permitted". Safety rating: MODERATE.

Is r-(Aspartyl Oligopeptide-162 Aspartyl rh-Polypeptide-48) allowed in the EU?

r-(Aspartyl Oligopeptide-162 Aspartyl rh-Polypeptide-48) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does r-(Aspartyl Oligopeptide-162 Aspartyl rh-Polypeptide-48) do in cosmetics?

r-(Aspartyl Oligopeptide-162 Aspartyl rh-Polypeptide-48) functions as: Skin conditioning (recombinant fusion peptide; anti-ageing biotech active). It is classified as a cosmetic ingredient in our database. CAS number: Not assigned.

What is the Margin of Safety for r-(Aspartyl Oligopeptide-162 Aspartyl rh-Polypeptide-48)?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check r-(Aspartyl Oligopeptide-162 Aspartyl rh-Polypeptide-48) compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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