Elephantorrhiza Elephantina Root Extract

INCI: ELEPHANTORRHIZA ELEPHANTINA ROOT EXTRACT

CAS Number
Not assigned
Function
Skin conditioning (traditional use: dermatological diseases, wound healing)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” no CFR restriction; not CIR reviewed

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Oral toxicity studies in rats demonstrated significant changes in body weight, haematological and serum biochemical parameters, and histopathological changes in kidneys, lungs, liver, and spleen at high doses (200โ€“1600 mg/kg), indicating potential toxicity at certain dose levels and bioactive compounds requiring comprehensive dermal safety characterization before cosmetic use.

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Concern Level: High

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Elephantorrhiza Elephantina Root Extract safe in cosmetics?

Oral toxicity studies in rats demonstrated significant changes in body weight, haematological and serum biochemical parameters, and histopathological changes in kidneys, lungs, liver, and spleen at high doses (200โ€“1600 mg/kg), indicating potential toxicity at certain dose levels and bioactive compounds requiring comprehensive dermal safety characterization before cosmetic use. The EU classifies Elephantorrhiza Elephantina Root Extract as "permitted". Safety rating: MODERATE.

Is Elephantorrhiza Elephantina Root Extract allowed in the EU?

Elephantorrhiza Elephantina Root Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Elephantorrhiza Elephantina Root Extract do in cosmetics?

Elephantorrhiza Elephantina Root Extract functions as: Skin conditioning (traditional use: dermatological diseases, wound healing). It is classified as a cosmetic ingredient in our database. CAS number: Not assigned.

What is the Margin of Safety for Elephantorrhiza Elephantina Root Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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