r-(Aspartyl Oligopeptide-162 Hexapeptide-40 Aspartyl rh-Polypeptide-114)

INCI: R-(ASPARTYL OLIGOPEPTIDE-162 HEXAPEPTIDE-40 ASPARTYL RH-POLYPEPTIDE-114)

CAS Number
Not assigned
Function
Skin conditioning — stimulates skin regeneration, strengthens skin structure, contributes to visible reduction of wrinkles
Safety Rating
POOR

Regulatory Status

🇪🇺 EU Status prohibited
🇺🇸 US Status prohibited
US Notes Not specifically banned; manufacturer responsibility for safety substantiation

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Listed as EU-prohibited ingredient ("INGREDIENTE PROHIBIDO por la UE"); produced by CHO cell fermentation with fused gene sequences for Oligopeptide-162, Hexapeptide-40, and rh-Polypeptide-114; initiation codon for aspartic acid . Do not use in EU-marketed products without definitive regulatory clearance.

⚠️
Concern Level: High

Frequently Asked Questions

Is r-(Aspartyl Oligopeptide-162 Hexapeptide-40 Aspartyl rh-Polypeptide-114) safe in cosmetics?

Listed as EU-prohibited ingredient ("INGREDIENTE PROHIBIDO por la UE"); produced by CHO cell fermentation with fused gene sequences for Oligopeptide-162, Hexapeptide-40, and rh-Polypeptide-114; initiation codon for aspartic acid . Do not use in EU-marketed products without definitive regulatory clearance. The EU classifies r-(Aspartyl Oligopeptide-162 Hexapeptide-40 Aspartyl rh-Polypeptide-114) as "prohibited". Safety rating: POOR.

Is r-(Aspartyl Oligopeptide-162 Hexapeptide-40 Aspartyl rh-Polypeptide-114) allowed in the EU?

r-(Aspartyl Oligopeptide-162 Hexapeptide-40 Aspartyl rh-Polypeptide-114) EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does r-(Aspartyl Oligopeptide-162 Hexapeptide-40 Aspartyl rh-Polypeptide-114) do in cosmetics?

r-(Aspartyl Oligopeptide-162 Hexapeptide-40 Aspartyl rh-Polypeptide-114) functions as: Skin conditioning — stimulates skin regeneration, strengthens skin structure, contributes to visible reduction of wrinkles. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned.

What is the Margin of Safety for r-(Aspartyl Oligopeptide-162 Hexapeptide-40 Aspartyl rh-Polypeptide-114)?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

📱

Is r-(Aspartyl Oligopeptide-162 Hexapeptide-40 Aspartyl rh-Polypeptide-114) in Your Products?

Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free →

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for r-(Aspartyl Oligopeptide-162 Hexapeptide-40 Aspartyl rh-Polypeptide-114) in your formulation.