r-(Methionyl sh-Oligopeptide-1 Oligopeptide-164)

INCI: R-(METHIONYL SH-OLIGOPEPTIDE-1 OLIGOPEPTIDE-164)

CAS Number
Not assigned (no public CAS registered)
Function
Skin conditioning, anti-aging (EGF-based component via sh-Oligopeptide-1)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No specific FDA monograph; permitted under general cosmetic use provisions; no GRAS or OTC status

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

sh-Oligopeptide-1 = synthetic EGF; PubMed review concluded clinical studies lack scientific basis for preclinical bioactivity; long-term risks unknown . No CAS assigned = traceability gap.

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Concern Level: Moderate

Frequently Asked Questions

Is r-(Methionyl sh-Oligopeptide-1 Oligopeptide-164) safe in cosmetics?

sh-Oligopeptide-1 = synthetic EGF; PubMed review concluded clinical studies lack scientific basis for preclinical bioactivity; long-term risks unknown . No CAS assigned = traceability gap. The EU classifies r-(Methionyl sh-Oligopeptide-1 Oligopeptide-164) as "restricted". Safety rating: MODERATE.

Is r-(Methionyl sh-Oligopeptide-1 Oligopeptide-164) allowed in the EU?

r-(Methionyl sh-Oligopeptide-1 Oligopeptide-164) EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does r-(Methionyl sh-Oligopeptide-1 Oligopeptide-164) do in cosmetics?

r-(Methionyl sh-Oligopeptide-1 Oligopeptide-164) functions as: Skin conditioning, anti-aging (EGF-based component via sh-Oligopeptide-1). It is classified as a cosmetic ingredient in our database. CAS number: Not assigned (no public CAS registered).

What is the Margin of Safety for r-(Methionyl sh-Oligopeptide-1 Oligopeptide-164)?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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