Raphanus Sativus Leaf Extract

INCI: RAPHANUS SATIVUS LEAF EXTRACT

CAS Number
84775-94-0 (species-level CAS for R. sativus extract)
Function
Humectant
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” CIR (2022) concluded radish-derived ingredients safe in present practices of use when formulated to be non-sensitizing

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Contains isothiocyanates (potential sensitizers/irritants) and potentially anthocyanins; CIR explicitly advises "formulated to be non-sensitizing"; leaf extract is less studied than root extract โ€” the CIR monograph covers root derivatives, not leaf; occupational case reports include IgE-mediated anaphylaxis and vesiculo-bullous dermatitis from contact with radish

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Concern Level: Moderate

Regulatory Flags

plant-extract potential-allergen

Frequently Asked Questions

Is Raphanus Sativus Leaf Extract safe in cosmetics?

Contains isothiocyanates (potential sensitizers/irritants) and potentially anthocyanins; CIR explicitly advises "formulated to be non-sensitizing"; leaf extract is less studied than root extract โ€” the CIR monograph covers root derivatives, not leaf; occupational case reports include IgE-mediated anaphylaxis and vesiculo-bullous dermatitis from contact with radish The EU classifies Raphanus Sativus Leaf Extract as "permitted". Safety rating: GOOD.

Is Raphanus Sativus Leaf Extract allowed in the EU?

Raphanus Sativus Leaf Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Raphanus Sativus Leaf Extract do in cosmetics?

Raphanus Sativus Leaf Extract functions as: Humectant. It is classified as a cosmetic ingredient in our database. CAS number: 84775-94-0 (species-level CAS for R. sativus extract).

What is the Margin of Safety for Raphanus Sativus Leaf Extract?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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