SH-Heptapeptide-1

INCI: SH-HEPTAPEPTIDE-1

CAS Number
Not assigned / not publicly listed
Function
Skin conditioning; related to Nrf2 pathway activation (antioxidant defense, anti-aging)
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No specific restriction; no CIR review

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Better data available than most on this list but still no CIR monograph. Nrf2 activation claims should be supported by in-vivo efficacy data. Verify supplier provides HRIPT data.

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Concern Level: Low

Frequently Asked Questions

Is SH-Heptapeptide-1 safe in cosmetics?

Better data available than most on this list but still no CIR monograph. Nrf2 activation claims should be supported by in-vivo efficacy data. Verify supplier provides HRIPT data. The EU classifies SH-Heptapeptide-1 as "permitted". Safety rating: GOOD.

Is SH-Heptapeptide-1 allowed in the EU?

SH-Heptapeptide-1 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does SH-Heptapeptide-1 do in cosmetics?

SH-Heptapeptide-1 functions as: Skin conditioning; related to Nrf2 pathway activation (antioxidant defense, anti-aging). It is classified as a cosmetic ingredient in our database. CAS number: Not assigned / not publicly listed.

What is the Margin of Safety for SH-Heptapeptide-1?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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