SH-DNA

CAS Number
Not assigned / not publicly listed
Function
Skin conditioning; synthetic human DNA oligonucleotide for cosmetic use
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No specific restriction; no CIR review. FDA does not specifically regulate DNA-based cosmetic actives differently, but gene-therapy claims would trigger drug classification

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Novel biotech ingredient class. Potential regulatory scrutiny if product claims approach gene therapy/gene expression territory. No CIR assessment. Requires careful claim substantiation to avoid drug misbranding.

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Concern Level: Moderate

Frequently Asked Questions

Is SH-DNA safe in cosmetics?

Novel biotech ingredient class. Potential regulatory scrutiny if product claims approach gene therapy/gene expression territory. No CIR assessment. Requires careful claim substantiation to avoid drug misbranding. The EU classifies SH-DNA as "permitted". Safety rating: MODERATE.

Is SH-DNA allowed in the EU?

SH-DNA EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does SH-DNA do in cosmetics?

SH-DNA functions as: Skin conditioning; synthetic human DNA oligonucleotide for cosmetic use. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned / not publicly listed.

What is the Margin of Safety for SH-DNA?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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