Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
4 study endpoints found for Silver Hydroxide. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 30 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 1.5 mg/kg bw/day | other | rat | oral | REACH |
| NOAEL | 30 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 1.5 mg/kg bw/day | other | rat | oral | REACH |
Expert Verdict
Silver CMR Cat. 2; highly reactive/unstable compound (decomposes to silver oxide); free silver ion release concern; argyria risk with overexposure; no formal cosmetic safety dossier
Frequently Asked Questions
Is Silver Hydroxide safe in cosmetics?
Silver CMR Cat. 2; highly reactive/unstable compound (decomposes to silver oxide); free silver ion release concern; argyria risk with overexposure; no formal cosmetic safety dossier The EU classifies Silver Hydroxide as "restricted". Safety rating: MODERATE. 4 toxicological study endpoint(s) are available in our database.
Is Silver Hydroxide allowed in the EU?
Silver Hydroxide EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does Silver Hydroxide do in cosmetics?
Silver Hydroxide functions as: Antimicrobial. It is classified as a cosmetic ingredient in our database. CAS number: 20667-12-3.
What is the Margin of Safety for Silver Hydroxide?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Silver Hydroxide?
The NOAEL (No Observed Adverse Effect Level) for Silver Hydroxide is 30 mg/kg bw/day based on a oral study via oral route in rat. A total of 4 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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