Silymarin

INCI: SILYMARIN

Function
Antioxidant, skin conditioning, anti-inflammatory
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not restricted by FDA for cosmetic use; also has GRAS history in dietary supplements

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

GHS hazard classifications (H315, H319, H335) apply to raw powder handling, not finished formulations at typical use levels (0.1โ€“1%). Individuals with Asteraceae allergies should patch-test.

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Concern Level: Low

Frequently Asked Questions

Is Silymarin safe in cosmetics?

GHS hazard classifications (H315, H319, H335) apply to raw powder handling, not finished formulations at typical use levels (0.1โ€“1%). Individuals with Asteraceae allergies should patch-test. The EU classifies Silymarin as "permitted". Safety rating: GOOD.

Is Silymarin allowed in the EU?

Silymarin EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Silymarin do in cosmetics?

Silymarin functions as: Antioxidant, skin conditioning, anti-inflammatory. It is classified as a cosmetic ingredient in our database.

What is the Margin of Safety for Silymarin?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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