Sodium C12-15 Pareth-3 Sulfate
INCI: SODIUM C12-15 ALKETH-3 SULFATE (FORMERLY SODIUM C12-15 PARETH-3 SULFATE)
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
10 study endpoints found for Sodium C12-15 Pareth-3 Sulfate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | >=300 mg/kg bw/day | oral | rat | oral | REACH |
| NOEL | >=1 other | oral | rat | oral | REACH |
| NOAEL | >225 mg/kg bw/day | oral | rat | oral | REACH |
| NOEL | 2.38 other | dermal | code:3543 | dermal | REACH |
| NOEL | 2.38 other | dermal | code:3543 | dermal | REACH |
| NOAEL | >225 mg/kg bw/day | oral | rat | oral | REACH |
| NOEL | 3 other | dermal | code:3484 | dermal | REACH |
| NOEL | 3 other | dermal | code:3484 | dermal | REACH |
| NOEL | 3 other | dermal | code:3484 | dermal | REACH |
| NOAEL | 300 mg/kg bw/day | oral | - | oral | REACH |
Expert Verdict
Higher irritation potential than >5 EO versions; 1,4-dioxane residual from ethoxylation; must be formulated to be non-irritating per CIR; INCI name updated to "Alketh" convention
Frequently Asked Questions
Is Sodium C12-15 Pareth-3 Sulfate safe in cosmetics?
Higher irritation potential than >5 EO versions; 1,4-dioxane residual from ethoxylation; must be formulated to be non-irritating per CIR; INCI name updated to "Alketh" convention The EU classifies Sodium C12-15 Pareth-3 Sulfate as "permitted". Safety rating: MODERATE. 10 toxicological study endpoint(s) are available in our database.
Is Sodium C12-15 Pareth-3 Sulfate allowed in the EU?
Sodium C12-15 Pareth-3 Sulfate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Sodium C12-15 Pareth-3 Sulfate do in cosmetics?
Sodium C12-15 Pareth-3 Sulfate functions as: Surfactant – Cleansing, Foaming Agent. It is classified as a cosmetic ingredient in our database. CAS number: 125301-92-0.
What is the Margin of Safety for Sodium C12-15 Pareth-3 Sulfate?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Sodium C12-15 Pareth-3 Sulfate?
The NOAEL (No Observed Adverse Effect Level) for Sodium C12-15 Pareth-3 Sulfate is >=300 mg/kg bw/day based on a oral study via oral route in rat. A total of 10 study endpoints are available. Source: REACH.
Compliance Tools
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