Dodoxynol-13

INCI: DODOXYNOL-13

CAS Number
9014-92-0 (same generic CAS as dodoxynol series)
Function
Surfactant-emulsifying, cleansing
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” not restricted under 21 CFR

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Dodoxynol-13 has a slightly better safety profile than Dodoxynol-12 due to higher ethoxylation degree (lower irritation, lower dermal penetration), but shares the same endocrine disruptor degradation concern and REACH environmental restrictions, making it ineligible for COSMOS/ECOCERT certification.

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Concern Level: Moderate

Frequently Asked Questions

Is Dodoxynol-13 safe in cosmetics?

Dodoxynol-13 has a slightly better safety profile than Dodoxynol-12 due to higher ethoxylation degree (lower irritation, lower dermal penetration), but shares the same endocrine disruptor degradation concern and REACH environmental restrictions, making it ineligible for COSMOS/ECOCERT certification. The EU classifies Dodoxynol-13 as "permitted". Safety rating: MODERATE.

Is Dodoxynol-13 allowed in the EU?

Dodoxynol-13 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Dodoxynol-13 do in cosmetics?

Dodoxynol-13 functions as: Surfactant-emulsifying, cleansing. It is classified as a cosmetic ingredient in our database. CAS number: 9014-92-0 (same generic CAS as dodoxynol series).

What is the Margin of Safety for Dodoxynol-13?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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