Sodium Cholate

INCI: SODIUM CHOLATE

CAS Number
361-09-1
Function
Surfactant–emulsifying, skin conditioning, solubilizing agent (bile salt)
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted; bile salts are also used in pharmaceutical applications as penetration enhancers

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
high
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Penetration enhancement activity — can increase absorption of other ingredients (positive or negative depending on formulation intent); irritation potential at concentrations >1%; animal-derived (bovine/porcine bile) — not suitable for vegan claims

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Concern Level: Moderate

Frequently Asked Questions

Is Sodium Cholate safe in cosmetics?

Penetration enhancement activity — can increase absorption of other ingredients (positive or negative depending on formulation intent); irritation potential at concentrations >1%; animal-derived (bovine/porcine bile) — not suitable for vegan claims The EU classifies Sodium Cholate as "permitted". Safety rating: MODERATE.

Is Sodium Cholate allowed in the EU?

Sodium Cholate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Sodium Cholate do in cosmetics?

Sodium Cholate functions as: Surfactant–emulsifying, skin conditioning, solubilizing agent (bile salt). It is classified as a cosmetic ingredient in our database. CAS number: 361-09-1.

What is the Margin of Safety for Sodium Cholate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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