Sodium Deoxycholate

INCI: SODIUM DEOXYCHOLATE

CAS Number
302-95-4
Function
Skin Conditioning, Emulsifying, Solubilizing (bile salt surfactant)
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted for cosmetic use; also FDA-approved as pharmaceutical ingredient (Kybella®); cosmetic use range 0.1–2%

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
high
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Skin irritation at >5%; H302 (harmful if swallowed); H315 (skin irritation); H319 (eye irritation) ; hepatotoxicity concern at parenteral doses

⚠️
Concern Level: High

Frequently Asked Questions

Is Sodium Deoxycholate safe in cosmetics?

Skin irritation at >5%; H302 (harmful if swallowed); H315 (skin irritation); H319 (eye irritation) ; hepatotoxicity concern at parenteral doses The EU classifies Sodium Deoxycholate as "permitted". Safety rating: MODERATE.

Is Sodium Deoxycholate allowed in the EU?

Sodium Deoxycholate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Sodium Deoxycholate do in cosmetics?

Sodium Deoxycholate functions as: Skin Conditioning, Emulsifying, Solubilizing (bile salt surfactant). It is classified as a cosmetic ingredient in our database. CAS number: 302-95-4.

What is the Margin of Safety for Sodium Deoxycholate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

📱

Is Sodium Deoxycholate in Your Products?

Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free →

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Sodium Deoxycholate in your formulation.