Good Cosmetic Ingredient NOAEL Data

Sodium EDTMP

INCI: SODIUM EDTMP

CAS Number
22036-77-7
Function
Chelating agent
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted for cosmetic use

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

2 study endpoints found for Sodium EDTMP. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 15 mg/kg bw/day oral rat oral REACH
LOAEL 15 mg/kg bw/day oral mouse oral REACH

Expert Verdict

Phosphonate-based chelator; environmental persistence concerns due to phosphonate backbone; less commonly used than EDTA

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Concern Level: Low

Frequently Asked Questions

Is Sodium EDTMP safe in cosmetics?

Phosphonate-based chelator; environmental persistence concerns due to phosphonate backbone; less commonly used than EDTA The EU classifies Sodium EDTMP as "permitted". Safety rating: GOOD. 2 toxicological study endpoint(s) are available in our database.

Is Sodium EDTMP allowed in the EU?

Sodium EDTMP EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Sodium EDTMP do in cosmetics?

Sodium EDTMP functions as: Chelating agent. It is classified as a cosmetic ingredient in our database. CAS number: 22036-77-7.

What is the Margin of Safety for Sodium EDTMP?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Sodium EDTMP?

The NOAEL (No Observed Adverse Effect Level) for Sodium EDTMP is 15 mg/kg bw/day based on a oral study via oral route in rat. A total of 2 study endpoints are available. Source: REACH.

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