NOAEL Studies Cosmetic Ingredient

Sodium Isethionate NOAEL Studies

INCI: SODIUM ISETHIONATE

CAS: 1562-00-1

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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NTP_ICE_acute_oral 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
NTP_ICE_acute_oral LD50 >5000 mg/kg bw Rat oral acute Rat Acute Oral Toxicity record_id=acute_oral_3081; row=12042; data_type=In Vivo; mixture=Chemical; chemical_name=Sodium 2-hydroxyethanesulfonate; preferred_name=Sodium 2-hydroxyethanesulfonate; dtxsid=DTXSID7027413; url_comptox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID7027413; source_file=acute_oral.xlsx
ToxValDB_ECHA_IUCLID 2 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_ECHA_IUCLID NOAEL =200 mg/kg bw/day Rat oral chronic; 91 days chronic QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7cb33e4b0a7c65d225371; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/en/registration-dossier/-/registered-dossier/23426?documentUUID=895e2cce-f794-48a7-9807-706381e09505; YEAR=2007; ORIGINAL_YEAR=2007; STUDY_GROUP=ECHA IUCLID_dup_Repeated Dose Toxicity Oral_15830433_15830434:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_0352afe8158b71141993d626d7919e50
ToxValDB_ECHA_IUCLID NOAEL =426 mg/kg bw/day Rat oral chronic; 91 days chronic QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7cb33e4b0a7c65d225371; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/en/registration-dossier/-/registered-dossier/23426?documentUUID=895e2cce-f794-48a7-9807-706381e09505; YEAR=2007; ORIGINAL_YEAR=2007; STUDY_GROUP=ECHA IUCLID_dup_Repeated Dose Toxicity Oral_15830433_15830434:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_fbea93e4f84bb793b586a29956db00a8
ToxValDB_GESTIS_DNEL 2 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_GESTIS_DNEL DNEL systemic =17.6 mg/m3 Human inhalation - Toxicity Value STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6543dd69e4b045b9ff7cd87e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.dguv.de/ifa/gestis/gestis-dnel-liste/index-2.jsp; STUDY_GROUP=GESTIS DNEL_dup_-_15632677_15632678:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_453369ec502b90d90a28a230c518f641
ToxValDB_GESTIS_DNEL DNEL systemic =35.3 mg/m3 Human inhalation - Toxicity Value STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6543dd69e4b045b9ff7cd87e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.dguv.de/ifa/gestis/gestis-dnel-liste/index-2.jsp; STUDY_GROUP=GESTIS DNEL_dup_-_15632677_15632678:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_c04605eb4765b7f41918c3745cdc901f
openFDA substances 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier 3R36J71C17 UNII - - - chemical {"approval_status":null,"molecular_formula":"C2H5O4S.Na","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"3R36J71C17"}
openFDA substances FDA UNII substance identifier 3R36J71C17 UNII - - - chemical {"approval_status":null,"molecular_formula":"C2H5O4S.Na","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"3R36J71C17"}
openFDA substances FDA UNII substance identifier 3R36J71C17 UNII - - - chemical {"approval_status":null,"molecular_formula":"C2H5O4S.Na","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"3R36J71C17"}
openFDA substances FDA UNII substance identifier 3R36J71C17 UNII - - - chemical {"approval_status":null,"molecular_formula":"C2H5O4S.Na","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"3R36J71C17"}