NOAEL Studies Surfactant

SODIUM LAURYL SULFATE NOAEL Studies

CAS: 151-21-3

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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COSMOS DB 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
COSMOS DB NOAEL 500 mg/kg bw/day rat oral 704 day Carcinogenicity US FDA CFSAN PAFA; US FDA CFSAN PAFA Study
COSMOS DB NOAEL 333 mg/kg bw/day rat oral 90 day Subchronic US FDA CFSAN PAFA; US FDA CFSAN PAFA Study
COSMOS DB NOAEL 2000 mg/kg bw/day rat oral 112 day Subchronic US FDA CFSAN PAFA; US FDA CFSAN PAFA Study
COSMOS DB NOAEL 2500 mg/kg bw/day mouse oral 28 day Short Term Toxicity US FDA CFSAN PAFA; US FDA CFSAN PAFA Study
NTP ICE acute inhalation 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
NTP ICE acute inhalation LC50 >3.9 mg/L - Inhalation Duration=1 hr In Vivo; AcuteInhalNICEATM; Rat Acute Inhalation Toxicity sheet=Data; excel_row=1060; Record_ID=acute_inhalation_3094; Data_Type=In Vivo; Internal_Data_Source=AcuteInhalNICEATM; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=Rat Acute Inhalation Toxicity; Endpoint=LC50; Response_Modifier=>; Response=3.9; Response_Unit=mg/L; Reference=ChemIDplus; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE endocrine 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
NTP ICE endocrine Model Score 0 unitless - - - ARPathway2016; AR Pathway Model, Antagonist sheet=Integrated_approaches; excel_row=14522; RecordID=ARPathway2016_885; DatasetName=ARPathway2016; DTXSID=DTXSID1026031; Assay=AR Pathway Model, Antagonist; Endpoint=Model Score; Response=0; Response_Unit=Unitless; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE eye irritation 6 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
NTP ICE eye irritation Draize rabbit irritation score 59.2 unitless Rabbit Ocular - In Vivo; Draize Eye Irritation/Corrosion Test sheet=Data; excel_row=582; Record_ID=eye_irritation_209; Data_Type=In Vivo; Concentration=15.0; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=Draize Eye Irritation/Corrosion Test; Endpoint=Draize rabbit irritation score; Response=59.2; Response_Unit=Unitless; Species=Rabbit; PMID=26472347.0; Reference=Yamaguchi et al. 2016; URL=10.1002/jat.3254; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE eye irritation EPA Classification 3 unitless Rabbit Ocular - In Vivo; Draize Eye Irritation/Corrosion Test sheet=Data; excel_row=577; Record_ID=eye_irritation_93; Data_Type=In Vivo; Concentration=3.0; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=Draize Eye Irritation/Corrosion Test; Endpoint=EPA Classification; Response=3; Response_Unit=Unitless; Species=Rabbit; Reference=ICCVAM 2006; URL=https://ntp.niehs.nih.gov/sites/default/files/iccvam/docs/ocutox_docs/oteval/otevalrpt.pdf; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE eye irritation GHS Classification 1 unitless Rabbit Ocular - In Vivo; Draize Eye Irritation/Corrosion Test sheet=Data; excel_row=581; Record_ID=eye_irritation_209; Data_Type=In Vivo; Concentration=15.0; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=Draize Eye Irritation/Corrosion Test; Endpoint=GHS Classification; Response=1; Response_Unit=Unitless; Species=Rabbit; PMID=26472347.0; Reference=Yamaguchi et al. 2016; URL=10.1002/jat.3254; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE eye irritation Intensity 0.7 %/sec - Ocular - In Vitro; Vitrigel sheet=Data; excel_row=583; Record_ID=eye_irritation_1315; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=Vitrigel; Endpoint=Intensity; Response=0.7; Response_Unit=%/sec; PMID=26472347.0; Reference=Yamaguchi et al. 2016; URL=10.1002/jat.3254; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE eye irritation Lag time 0 s - Ocular - In Vitro; Vitrigel sheet=Data; excel_row=578; Record_ID=eye_irritation_1315; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=Vitrigel; Endpoint=Lag time; Response=0; Response_Unit=sec; PMID=26472347.0; Reference=Yamaguchi et al. 2016; URL=10.1002/jat.3254; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE eye irritation Plateau level 84 % - Ocular - In Vitro; Vitrigel sheet=Data; excel_row=576; Record_ID=eye_irritation_1315; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=Vitrigel; Endpoint=Plateau level; Response=84; Response_Unit=%; PMID=26472347.0; Reference=Yamaguchi et al. 2016; URL=10.1002/jat.3254; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation 150 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
NTP ICE skin irritation Breakthrough Time 16.15 min - Dermal - In Vitro; Corrositex sheet=Data_invitro; excel_row=1164; Record_ID=skin_irritation_invitro_166; Data_Type=In Vitro; Formulation_ID=MIX804; Formulation_Name=Sulfuric acid/ Sodium dodecyl sulfate; Percent_Active_Ingredient=10; Mixture=Mixture; DTXSID=DTXSID1026031; Assay=Corrositex; Endpoint=Breakthrough Time; Response=16.15; Response_Unit=min; Reference=ICCVAM 1999; Not available; ntp.niehs.nih.gov/iccvam/docs/dermal_docs/corprrep.pdf; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Breakthrough Time 32.1 min - Dermal - In Vitro; Corrositex sheet=Data_invitro; excel_row=1163; Record_ID=skin_irritation_invitro_165; Data_Type=In Vitro; Formulation_ID=MIX803; Formulation_Name=Sodium hydroxide/ Sodium dodecyl sulfate(1:10); Percent_Active_Ingredient=90; Mixture=Mixture; DTXSID=DTXSID1026031; Assay=Corrositex; Endpoint=Breakthrough Time; Response=32.1; Response_Unit=min; Reference=ICCVAM 1999; Not available; ntp.niehs.nih.gov/iccvam/docs/dermal_docs/corprrep.pdf; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Breakthrough Time 140 min - Dermal - In Vitro; Corrositex sheet=Data_invitro; excel_row=1032; Record_ID=skin_irritation_invitro_73; Data_Type=In Vitro; Formulation_ID=MIX787; Formulation_Name=Empicol LZPV/C; Mixture=Mixture; DTXSID=DTXSID1026031; Assay=Corrositex; Endpoint=Breakthrough Time; Response=140; Response_Unit=min; Reference=Botham et al. 1995; Not available; 10.1177/026119299502300207; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Breakthrough Time 240 min - Dermal - In Vitro; Corrositex sheet=Data_invitro; excel_row=1031; Record_ID=skin_irritation_invitro_74; Data_Type=In Vitro; Formulation_ID=MIX787; Formulation_Name=Empicol LZPV/C; Mixture=Mixture; DTXSID=DTXSID1026031; Assay=Corrositex; Endpoint=Breakthrough Time; Response=240; Response_Unit=min; Reference=Botham et al. 1995; Not available; 10.1177/026119299502300207; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation ET50 37.9 min - Dermal - In Vitro; EpiDerm Irritation sheet=Data_invitro; excel_row=1294; Record_ID=skin_irritation_invitro_1517; Data_Type=In Vitro; Formulation_Name=SLS (20%); Concentration=20; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=EpiDerm Irritation; Endpoint=ET50; Response=37.9; Response_Unit=min; Reference=Fentem et al. 2001; 11259870; 10.1016/s0887-2333(01)00002-9; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation ET50 42.9 min - Dermal - In Vitro; EpiDerm Irritation sheet=Data_invitro; excel_row=1295; Record_ID=skin_irritation_invitro_1519; Data_Type=In Vitro; Formulation_Name=SLS (20%); Concentration=20; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=EpiDerm Irritation; Endpoint=ET50; Response=42.9; Response_Unit=min; Reference=Fentem et al. 2001; 11259870; 10.1016/s0887-2333(01)00002-9; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation ET50 44.9 min - Dermal - In Vitro; EpiDerm Irritation sheet=Data_invitro; excel_row=1167; Record_ID=skin_irritation_invitro_1520; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (50%); Concentration=50; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=EpiDerm Irritation; Endpoint=ET50; Response=44.9; Response_Unit=min; Reference=Fentem et al. 2001; 11259870; 10.1016/s0887-2333(01)00002-9; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation ET50 50.2 min - Dermal - In Vitro; EpiDerm Irritation sheet=Data_invitro; excel_row=1168; Record_ID=skin_irritation_invitro_1521; Data_Type=In Vitro; Formulation_Name=SLS (20%); Concentration=20; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=EpiDerm Irritation; Endpoint=ET50; Response=50.2; Response_Unit=min; Reference=Fentem et al. 2001; 11259870; 10.1016/s0887-2333(01)00002-9; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation ET50 51.9 min - Dermal - In Vitro; EpiDerm Irritation sheet=Data_invitro; excel_row=1169; Record_ID=skin_irritation_invitro_1523; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (50%); Concentration=50; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=EpiDerm Irritation; Endpoint=ET50; Response=51.9; Response_Unit=min; Reference=Fentem et al. 2001; 11259870; 10.1016/s0887-2333(01)00002-9; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation ET50 76.8 min - Dermal - In Vitro; EpiDerm Irritation sheet=Data_invitro; excel_row=1170; Record_ID=skin_irritation_invitro_1524; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (50%); Concentration=50; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=EpiDerm Irritation; Endpoint=ET50; Response=76.8; Response_Unit=min; Reference=Fentem et al. 2001; 11259870; 10.1016/s0887-2333(01)00002-9; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation ET50 93.5 min - Dermal - In Vitro; EpiDerm Irritation sheet=Data_invitro; excel_row=1293; Record_ID=skin_irritation_invitro_1526; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (50%); Concentration=50; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=EpiDerm Irritation; Endpoint=ET50; Response=93.5; Response_Unit=min; Reference=Fentem et al. 2001; 11259870; 10.1016/s0887-2333(01)00002-9; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation ET50 95.6 min - Dermal - In Vitro; EpiDerm Irritation sheet=Data_invitro; excel_row=1034; Record_ID=skin_irritation_invitro_1528; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (50%); Concentration=50; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=EpiDerm Irritation; Endpoint=ET50; Response=95.6; Response_Unit=min; Reference=Fentem et al. 2001; 11259870; 10.1016/s0887-2333(01)00002-9; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation ET50 108 min - Dermal - In Vitro; EpiDerm Irritation sheet=Data_invitro; excel_row=1035; Record_ID=skin_irritation_invitro_1530; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (50%); Concentration=50; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=EpiDerm Irritation; Endpoint=ET50; Response=108; Response_Unit=min; Reference=Fentem et al. 2001; 11259870; 10.1016/s0887-2333(01)00002-9; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation ET50 116 min - Dermal - In Vitro; EpiDerm Irritation sheet=Data_invitro; excel_row=1036; Record_ID=skin_irritation_invitro_1532; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (50%); Concentration=50; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=EpiDerm Irritation; Endpoint=ET50; Response=116; Response_Unit=min; Reference=Fentem et al. 2001; 11259870; 10.1016/s0887-2333(01)00002-9; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation ET50 126 min - Dermal - In Vitro; EpiDerm Irritation sheet=Data_invitro; excel_row=1037; Record_ID=skin_irritation_invitro_1534; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (50%); Concentration=50; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=EpiDerm Irritation; Endpoint=ET50; Response=126; Response_Unit=min; Reference=Fentem et al. 2001; 11259870; 10.1016/s0887-2333(01)00002-9; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation ET50 139 min - Dermal - In Vitro; EpiDerm Irritation sheet=Data_invitro; excel_row=1038; Record_ID=skin_irritation_invitro_1537; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (50%); Concentration=50; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=EpiDerm Irritation; Endpoint=ET50; Response=139; Response_Unit=min; Reference=Fentem et al. 2001; 11259870; 10.1016/s0887-2333(01)00002-9; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Positive reaction 22.5 % Human Dermal - In Vivo; Four-hour Human Patch Test sheet=Data_invivo; excel_row=415; Record_ID=skin_irritation_invivo_59; Data_Type=In Vivo; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=Four-hour Human Patch Test; Endpoint=Positive reaction; Response=22.5; Response_Unit=%; Species=Human; Reference=Robinson et al. 2001; 11422260; 10.1034/j.1600-0536.2001.045001001.x; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Positive reaction 68.8 % Human Dermal - In Vivo; Four-hour Human Patch Test sheet=Data_invivo; excel_row=416; Record_ID=skin_irritation_invivo_61; Data_Type=In Vivo; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=Four-hour Human Patch Test; Endpoint=Positive reaction; Response=68.8; Response_Unit=%; Species=Human; Reference=Robinson et al. 2001; 11422260; 10.1034/j.1600-0536.2001.045001001.x; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Positive reaction 70.8 % Human Dermal - In Vivo; Four-hour Human Patch Test sheet=Data_invivo; excel_row=418; Record_ID=skin_irritation_invivo_90; Data_Type=In Vivo; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=Four-hour Human Patch Test; Endpoint=Positive reaction; Response=70.8; Response_Unit=%; Species=Human; Reference=Robinson et al. 2001; 11422260; 10.1034/j.1600-0536.2001.045001001.x; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Positive reaction 79.7 % Human Dermal - In Vivo; Four-hour Human Patch Test sheet=Data_invivo; excel_row=417; Record_ID=skin_irritation_invivo_89; Data_Type=In Vivo; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=Four-hour Human Patch Test; Endpoint=Positive reaction; Response=79.7; Response_Unit=%; Species=Human; Reference=Jirova et al. 2010; 20136894; 10.1111/j.1600-0536.2009.01640.x; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Positive reaction 83.1 % Human Dermal - In Vivo; Four-hour Human Patch Test sheet=Data_invivo; excel_row=413; Record_ID=skin_irritation_invivo_88; Data_Type=In Vivo; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=Four-hour Human Patch Test; Endpoint=Positive reaction; Response=83.1; Response_Unit=%; Species=Human; Reference=Basketter et al. 2004; 15291823; 10.1111/j.0105-1873.2004.00385.x; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation TER 1.4 kiloohms - Dermal - In Vitro; TER Corrosion sheet=Data_invitro; excel_row=1330; Record_ID=skin_irritation_invitro_2552; Data_Type=In Vitro; Formulation_ID=MIX787; Formulation_Name=Empicol LZPV/C; Mixture=Mixture; DTXSID=DTXSID1026031; Assay=TER Corrosion; Endpoint=TER; Response=1.4; Response_Unit=kiloohms; Reference=Botham et al. 1995; Not available; 10.1177/026119299502300207; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation TER 1.5 kiloohms - Dermal - In Vitro; TER Corrosion sheet=Data_invitro; excel_row=1329; Record_ID=skin_irritation_invitro_2551; Data_Type=In Vitro; Formulation_ID=MIX787; Formulation_Name=Empicol LZPV/C; Mixture=Mixture; DTXSID=DTXSID1026031; Assay=TER Corrosion; Endpoint=TER; Response=1.5; Response_Unit=kiloohms; Reference=Botham et al. 1995; Not available; 10.1177/026119299502300207; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 1.7 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1242; Record_ID=skin_irritation_invitro_727; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=1.7; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 1.8 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1221; Record_ID=skin_irritation_invitro_706; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=1.8; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 2 % - Dermal - In Vitro; EpiDerm Irritation sheet=Data_invitro; excel_row=1284; Record_ID=skin_irritation_invitro_960; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (50%); Concentration=50; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=EpiDerm Irritation; Endpoint=Viability; Response=2; Response_Unit=%; Reference=Zuang et al. 2002; 11827575; 10.1177/026119290203000110; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 2.1 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1190; Record_ID=skin_irritation_invitro_675; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=2.1; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 2.2 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1214; Record_ID=skin_irritation_invitro_699; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=2.20; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 2.3 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1175; Record_ID=skin_irritation_invitro_660; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=2.30; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 2.4 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1205; Record_ID=skin_irritation_invitro_690; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=2.4; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 2.5 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1192; Record_ID=skin_irritation_invitro_677; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=2.5; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 2.6 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1230; Record_ID=skin_irritation_invitro_715; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=2.6; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 2.62 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1186; Record_ID=skin_irritation_invitro_671; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=2.62; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 2.7 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1191; Record_ID=skin_irritation_invitro_676; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=2.7; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 2.8 % - Dermal - In Vitro; EpiDerm Irritation sheet=Data_invitro; excel_row=1285; Record_ID=skin_irritation_invitro_962; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (50%); Concentration=50; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=EpiDerm Irritation; Endpoint=Viability; Response=2.8; Response_Unit=%; Reference=Zuang et al. 2002; 11827575; 10.1177/026119290203000110; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 2.89 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1196; Record_ID=skin_irritation_invitro_681; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=2.89; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 2.9 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1208; Record_ID=skin_irritation_invitro_693; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=2.9; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 2.93 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1199; Record_ID=skin_irritation_invitro_684; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=2.93; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 3.1 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1201; Record_ID=skin_irritation_invitro_686; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=3.1; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 3.2 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1210; Record_ID=skin_irritation_invitro_695; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=3.2; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 3.3 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1171; Record_ID=skin_irritation_invitro_656; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=3.3; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 3.4 % - Dermal - In Vitro; EpiDerm Irritation sheet=Data_invitro; excel_row=1286; Record_ID=skin_irritation_invitro_964; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (50%); Concentration=50; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=EpiDerm Irritation; Endpoint=Viability; Response=3.4; Response_Unit=%; Reference=Zuang et al. 2002; 11827575; 10.1177/026119290203000110; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 3.49 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1180; Record_ID=skin_irritation_invitro_665; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=3.49; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 3.5 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1194; Record_ID=skin_irritation_invitro_679; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=3.5; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 3.51 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1224; Record_ID=skin_irritation_invitro_709; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=3.51; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 3.6 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1216; Record_ID=skin_irritation_invitro_701; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=3.6; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 3.8 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1219; Record_ID=skin_irritation_invitro_704; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=3.8; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 3.94 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1227; Record_ID=skin_irritation_invitro_712; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=3.94; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 3.97 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1228; Record_ID=skin_irritation_invitro_713; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=3.97; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 4.1 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1193; Record_ID=skin_irritation_invitro_678; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=4.10; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 4.2 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1211; Record_ID=skin_irritation_invitro_696; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=4.2; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 4.42 % - Dermal - In Vitro; EpiSkin Irritation sheet=Data_invitro; excel_row=1172; Record_ID=skin_irritation_invitro_657; Data_Type=In Vitro; Formulation_Name=SLS 50% (aq.); Concentration=50; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=EpiSkin Irritation; Endpoint=Viability; Response=4.42; Response_Unit=%; Reference=Cotovio et al. 2005; 16185103; 10.1177/026119290503300403; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 4.46 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1187; Record_ID=skin_irritation_invitro_672; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=4.46; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 4.7 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1251; Record_ID=skin_irritation_invitro_736; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=4.7; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 4.8 % - Dermal - In Vitro; EpiSkin Irritation sheet=Data_invitro; excel_row=1278; Record_ID=skin_irritation_invitro_949; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (50%); Concentration=50; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=EpiSkin Irritation; Endpoint=Viability; Response=4.8; Response_Unit=%; Reference=Fentem et al. 2001; 11259870; 10.1016/s0887-2333(01)00002-9; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 4.81 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1182; Record_ID=skin_irritation_invitro_667; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=4.81; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 5 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1225; Record_ID=skin_irritation_invitro_710; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=5; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 5.2 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1231; Record_ID=skin_irritation_invitro_716; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=5.2; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 5.4 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1240; Record_ID=skin_irritation_invitro_725; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=5.4; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 5.45 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1184; Record_ID=skin_irritation_invitro_669; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=5.45; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 5.6 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1241; Record_ID=skin_irritation_invitro_726; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=5.6; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 5.7 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1234; Record_ID=skin_irritation_invitro_719; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=5.7; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 5.9 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1198; Record_ID=skin_irritation_invitro_683; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=5.9; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 6 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1173; Record_ID=skin_irritation_invitro_658; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=6; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 6.1 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1174; Record_ID=skin_irritation_invitro_659; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=6.1; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 6.35 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1269; Record_ID=skin_irritation_invitro_931; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=6.35; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 6.4 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1223; Record_ID=skin_irritation_invitro_708; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=6.4; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 6.7 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1245; Record_ID=skin_irritation_invitro_730; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=6.7; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 7 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1176; Record_ID=skin_irritation_invitro_661; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=7; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 7.17 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1189; Record_ID=skin_irritation_invitro_674; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=7.17; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 7.22 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1260; Record_ID=skin_irritation_invitro_912; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=7.22; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 7.3 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1178; Record_ID=skin_irritation_invitro_663; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=7.3; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 7.4 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1246; Record_ID=skin_irritation_invitro_731; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=7.4; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 7.5 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1179; Record_ID=skin_irritation_invitro_664; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=7.5; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 7.6 % - Dermal - In Vitro; EpiSkin Irritation sheet=Data_invitro; excel_row=1279; Record_ID=skin_irritation_invitro_951; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (50%); Concentration=50; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=EpiSkin Irritation; Endpoint=Viability; Response=7.6; Response_Unit=%; Reference=Fentem et al. 2001; 11259870; 10.1016/s0887-2333(01)00002-9; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 7.7 % - Dermal - In Vitro; EpiDerm Irritation sheet=Data_invitro; excel_row=1266; Record_ID=skin_irritation_invitro_925; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (20% aq.); Concentration=20; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=EpiDerm Irritation; Endpoint=Viability; Response=7.7; Response_Unit=%; Reference=Kandarova et al. 2005; 16185104; 10.1177/026119290503300408; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 7.8 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1249; Record_ID=skin_irritation_invitro_734; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=7.8; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 8 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1235; Record_ID=skin_irritation_invitro_720; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=8; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 8.1 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1181; Record_ID=skin_irritation_invitro_666; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=8.1; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 8.2 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1207; Record_ID=skin_irritation_invitro_692; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=8.20; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 8.5 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1195; Record_ID=skin_irritation_invitro_680; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=8.5; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 8.8 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1200; Record_ID=skin_irritation_invitro_685; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=8.80; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 9.2 % - Dermal - In Vitro; EpiSkin Irritation sheet=Data_invitro; excel_row=1280; Record_ID=skin_irritation_invitro_953; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (50%); Concentration=50; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=EpiSkin Irritation; Endpoint=Viability; Response=9.20; Response_Unit=%; Reference=Fentem et al. 2001; 11259870; 10.1016/s0887-2333(01)00002-9; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 9.4 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1177; Record_ID=skin_irritation_invitro_662; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=9.4; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 9.6 % - Dermal - In Vitro; EpiDerm Irritation sheet=Data_invitro; excel_row=1263; Record_ID=skin_irritation_invitro_919; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (50%); Concentration=50; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=EpiDerm Irritation; Endpoint=Viability; Response=9.6; Response_Unit=%; Reference=Kandarova et al. 2004; 15329774; Not available|Kandarova et al. 2005; 16185104; 10.1177/026119290503300408; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 9.76 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1275; Record_ID=skin_irritation_invitro_943; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=9.76; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 9.9 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1226; Record_ID=skin_irritation_invitro_711; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=9.9; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 10.2 % - Dermal - In Vitro; EpiSkin Irritation sheet=Data_invitro; excel_row=1183; Record_ID=skin_irritation_invitro_668; Data_Type=In Vitro; Formulation_Name=SLS 20% (aq.); Concentration=20; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=EpiSkin Irritation; Endpoint=Viability; Response=10.20; Response_Unit=%; Reference=Cotovio et al. 2005; 16185103; 10.1177/026119290503300403; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 10.7 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1236; Record_ID=skin_irritation_invitro_721; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=10.7; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 10.8 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1212; Record_ID=skin_irritation_invitro_697; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=10.8; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 10.9 % - Dermal - In Vitro; EpiSkin Irritation sheet=Data_invitro; excel_row=1273; Record_ID=skin_irritation_invitro_939; Data_Type=In Vitro; Formulation_Name=soidum lauryl sulphate (50%); Concentration=50; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=EpiSkin Irritation; Endpoint=Viability; Response=10.9; Response_Unit=%; Reference=Portes et al. 2002; 12423661; 10.1016/s0887-2333(02)00090-5; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 11.7 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1204; Record_ID=skin_irritation_invitro_689; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=11.7; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 11.74 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1261; Record_ID=skin_irritation_invitro_915; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=11.74; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 12 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1248; Record_ID=skin_irritation_invitro_733; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=12; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 12.1 % - Dermal - In Vitro; EpiSkin Irritation sheet=Data_invitro; excel_row=1287; Record_ID=skin_irritation_invitro_966; Data_Type=In Vitro; Formulation_Name=Sodium dodecyl sulfate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=EpiSkin Irritation; Endpoint=Viability; Response=12.1; Response_Unit=%; Reference=Portes et al. 2002; 12423661; 10.1016/s0887-2333(02)00090-5; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 12.2 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1218; Record_ID=skin_irritation_invitro_703; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=12.2; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 12.3 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1250; Record_ID=skin_irritation_invitro_735; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=12.3; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 12.5 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1233; Record_ID=skin_irritation_invitro_718; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=12.5; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 12.6 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1243; Record_ID=skin_irritation_invitro_728; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=12.6; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 12.9 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1247; Record_ID=skin_irritation_invitro_732; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=12.9; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 13 % - Dermal - In Vitro; EpiSkin Irritation sheet=Data_invitro; excel_row=1288; Record_ID=skin_irritation_invitro_968; Data_Type=In Vitro; Formulation_Name=Sodium dodecyl sulfate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=EpiSkin Irritation; Endpoint=Viability; Response=13; Response_Unit=%; Reference=Portes et al. 2002; 12423661; 10.1016/s0887-2333(02)00090-5; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 13.9 % - Dermal - In Vitro; EpiSkin Irritation sheet=Data_invitro; excel_row=1289; Record_ID=skin_irritation_invitro_970; Data_Type=In Vitro; Formulation_Name=Sodium dodecyl sulfate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=EpiSkin Irritation; Endpoint=Viability; Response=13.9; Response_Unit=%; Reference=Portes et al. 2002; 12423661; 10.1016/s0887-2333(02)00090-5; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 14.08 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1262; Record_ID=skin_irritation_invitro_917; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=14.08; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 14.5 % - Dermal - In Vitro; EpiDerm Irritation sheet=Data_invitro; excel_row=1265; Record_ID=skin_irritation_invitro_923; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (50%); Concentration=50; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=EpiDerm Irritation; Endpoint=Viability; Response=14.5; Response_Unit=%; Reference=Kandarova et al. 2004; 15329774; Not available|Kandarova et al. 2005; 16185104; 10.1177/026119290503300408; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 14.7 % - Dermal - In Vitro; EpiSkin Irritation sheet=Data_invitro; excel_row=1282; Record_ID=skin_irritation_invitro_957; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (50%); Concentration=50; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=EpiSkin Irritation; Endpoint=Viability; Response=14.7; Response_Unit=%; Reference=Fentem et al. 2001; 11259870; 10.1016/s0887-2333(01)00002-9; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 15.67 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1270; Record_ID=skin_irritation_invitro_933; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=15.67; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 21.2 % - Dermal - In Vitro; EpiDerm Irritation sheet=Data_invitro; excel_row=1268; Record_ID=skin_irritation_invitro_929; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (20% aq.); Concentration=20; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=EpiDerm Irritation; Endpoint=Viability; Response=21.2; Response_Unit=%; Reference=Kandarova et al. 2005; 16185104; 10.1177/026119290503300408; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 27.55 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1271; Record_ID=skin_irritation_invitro_935; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=27.55; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 31.6 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1276; Record_ID=skin_irritation_invitro_945; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=31.6; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 34 % - Dermal - In Vitro; EpiSkin Irritation sheet=Data_invitro; excel_row=1274; Record_ID=skin_irritation_invitro_941; Data_Type=In Vitro; Formulation_Name=soidum lauryl sulphate (50%); Concentration=50; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=EpiSkin Irritation; Endpoint=Viability; Response=34; Response_Unit=%; Reference=Portes et al. 2002; 12423661; 10.1016/s0887-2333(02)00090-5; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 36.81 % - Dermal - In Vitro; EpiSkin Irritation sheet=Data_invitro; excel_row=1185; Record_ID=skin_irritation_invitro_670; Data_Type=In Vitro; Formulation_Name=SLS 50% (aq.); Concentration=50; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=EpiSkin Irritation; Endpoint=Viability; Response=36.81; Response_Unit=%; Reference=Cotovio et al. 2005; 16185103; 10.1177/026119290503300403; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 38.61 % - Dermal - In Vitro; LabCyte EPI-MODEL24 Irritation sheet=Data_invitro; excel_row=1277; Record_ID=skin_irritation_invitro_947; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (5%); Concentration=5; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte EPI-MODEL24 Irritation; Endpoint=Viability; Response=38.61; Response_Unit=%; Reference=Kojima et al. 2012; 22558976; 10.1177/026119291204000108; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 52 % - Dermal - In Vitro; EpiSkin Irritation sheet=Data_invitro; excel_row=1290; Record_ID=skin_irritation_invitro_972; Data_Type=In Vitro; Formulation_Name=Sodium dodecyl sulfate (1%); Concentration=1; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=EpiSkin Irritation; Endpoint=Viability; Response=52; Response_Unit=%; Reference=Portes et al. 2002; 12423661; 10.1016/s0887-2333(02)00090-5; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 53.1 % - Dermal - In Vitro; EpiSkin Irritation sheet=Data_invitro; excel_row=1291; Record_ID=skin_irritation_invitro_973; Data_Type=In Vitro; Formulation_Name=Sodium dodecyl sulfate (1%); Concentration=1; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=EpiSkin Irritation; Endpoint=Viability; Response=53.1; Response_Unit=%; Reference=Portes et al. 2002; 12423661; 10.1016/s0887-2333(02)00090-5; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 61.32 % - Dermal - In Vitro; EpiSkin Irritation sheet=Data_invitro; excel_row=1188; Record_ID=skin_irritation_invitro_673; Data_Type=In Vitro; Formulation_Name=SLS 20% (aq.); Concentration=20; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=EpiSkin Irritation; Endpoint=Viability; Response=61.32; Response_Unit=%; Reference=Cotovio et al. 2005; 16185103; 10.1177/026119290503300403; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 75.3 % - Dermal - In Vitro; EpiSkin Irritation sheet=Data_invitro; excel_row=1292; Record_ID=skin_irritation_invitro_975; Data_Type=In Vitro; Formulation_Name=Sodium dodecyl sulfate (1%); Concentration=1; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=EpiSkin Irritation; Endpoint=Viability; Response=75.3; Response_Unit=%; Reference=Portes et al. 2002; 12423661; 10.1016/s0887-2333(02)00090-5; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability 77.1 % - Dermal - In Vitro; EpiSkin Irritation sheet=Data_invitro; excel_row=1283; Record_ID=skin_irritation_invitro_958; Data_Type=In Vitro; Formulation_Name=Sodium lauryl sulphate (50%); Concentration=50; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=EpiSkin Irritation; Endpoint=Viability; Response=77.10; Response_Unit=%; Reference=Fentem et al. 2001; 11259870; 10.1016/s0887-2333(01)00002-9; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability (18 hours) 0.6 % - Dermal - In Vitro; Vitrolife-Skin Irritation sheet=Data_invitro; excel_row=1256; Record_ID=skin_irritation_invitro_761; Data_Type=In Vitro; Concentration=50; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=Vitrolife-Skin Irritation; Endpoint=Viability (18 hours); Response=0.6; Response_Unit=%; Reference=Morikawa et al. 2008; Not available; 10.11232/AATEX.13.11; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability (18 hours) 1.8 % - Dermal - In Vitro; Vitrolife-Skin Irritation sheet=Data_invitro; excel_row=1252; Record_ID=skin_irritation_invitro_760; Data_Type=In Vitro; Concentration=20; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=Vitrolife-Skin Irritation; Endpoint=Viability (18 hours); Response=1.8; Response_Unit=%; Reference=Morikawa et al. 2008; Not available; 10.11232/AATEX.13.11; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability (240 minutes) 79 % - Dermal - In Vitro; EpiSkin Corrosion sheet=Data_invitro; excel_row=1326; Record_ID=skin_irritation_invitro_2368; Data_Type=In Vitro; Concentration=20; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=EpiSkin Corrosion; Endpoint=Viability (240 minutes); Response=79; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability (240 minutes) 80.6 % - Dermal - In Vitro; EpiSkin Corrosion sheet=Data_invitro; excel_row=1328; Record_ID=skin_irritation_invitro_2372; Data_Type=In Vitro; Concentration=20; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=EpiSkin Corrosion; Endpoint=Viability (240 minutes); Response=80.60; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability (240 minutes) 94.2 % - Dermal - In Vitro; EpiSkin Corrosion sheet=Data_invitro; excel_row=1327; Record_ID=skin_irritation_invitro_2370; Data_Type=In Vitro; Concentration=20; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=EpiSkin Corrosion; Endpoint=Viability (240 minutes); Response=94.2; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability (3 minutes) 74.1 % - Dermal - In Vitro; EpiDerm Corrosion sheet=Data_invitro; excel_row=1319; Record_ID=skin_irritation_invitro_2356; Data_Type=In Vitro; Concentration=20; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=EpiDerm Corrosion; Endpoint=Viability (3 minutes); Response=74.10; Response_Unit=%; Reference=Liebsch et al. 2000; 25419920; 10.1177/026119290002800309; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability (3 minutes) 76.4 % - Dermal - In Vitro; EpiDerm Corrosion sheet=Data_invitro; excel_row=1296; Record_ID=skin_irritation_invitro_2360; Data_Type=In Vitro; Concentration=20; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=EpiDerm Corrosion; Endpoint=Viability (3 minutes); Response=76.40; Response_Unit=%; Reference=Liebsch et al. 2000; 25419920; 10.1177/026119290002800309; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability (3 minutes) 80.3 % - Dermal - In Vitro; EpiDerm Corrosion sheet=Data_invitro; excel_row=1322; Record_ID=skin_irritation_invitro_2364; Data_Type=In Vitro; Concentration=20; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=EpiDerm Corrosion; Endpoint=Viability (3 minutes); Response=80.3; Response_Unit=%; Reference=Liebsch et al. 2000; 25419920; 10.1177/026119290002800309; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability (3 minutes) 85.2 % - Dermal - In Vitro; SkinEthic Corrosion sheet=Data_invitro; excel_row=1312; Record_ID=skin_irritation_invitro_2336; Data_Type=In Vitro; Concentration=20; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=SkinEthic Corrosion; Endpoint=Viability (3 minutes); Response=85.2; Response_Unit=%; Reference=Tornier et al. 2010; 20471469; 10.1016/j.tiv.2010.05.005; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability (3 minutes) 89 % - Dermal - In Vitro; EpiSkin Corrosion sheet=Data_invitro; excel_row=1318; Record_ID=skin_irritation_invitro_2372; Data_Type=In Vitro; Concentration=20; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=EpiSkin Corrosion; Endpoint=Viability (3 minutes); Response=89; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability (3 minutes) 89.3 % - Dermal - In Vitro; EpiDerm Corrosion sheet=Data_invitro; excel_row=1321; Record_ID=skin_irritation_invitro_2362; Data_Type=In Vitro; Concentration=20; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=EpiDerm Corrosion; Endpoint=Viability (3 minutes); Response=89.3; Response_Unit=%; Reference=Liebsch et al. 2000; 25419920; 10.1177/026119290002800309; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability (3 minutes) 90.6 % - Dermal - In Vitro; EpiDerm Corrosion sheet=Data_invitro; excel_row=1320; Record_ID=skin_irritation_invitro_2358; Data_Type=In Vitro; Concentration=20; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=EpiDerm Corrosion; Endpoint=Viability (3 minutes); Response=90.6; Response_Unit=%; Reference=Liebsch et al. 2000; 25419920; 10.1177/026119290002800309; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability (3 minutes) 99.3 % - Dermal - In Vitro; SkinEthic Corrosion sheet=Data_invitro; excel_row=1311; Record_ID=skin_irritation_invitro_2313; Data_Type=In Vitro; Concentration=20; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=SkinEthic Corrosion; Endpoint=Viability (3 minutes); Response=99.3; Response_Unit=%; Reference=Kandarova et al. 2006; 16455230; 10.1016/j.tiv.2005.11.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability (3 minutes) 99.6 % - Dermal - In Vitro; SkinEthic Corrosion sheet=Data_invitro; excel_row=1310; Record_ID=skin_irritation_invitro_2334; Data_Type=In Vitro; Concentration=20; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=SkinEthic Corrosion; Endpoint=Viability (3 minutes); Response=99.6; Response_Unit=%; Reference=Tornier et al. 2010; 20471469; 10.1016/j.tiv.2010.05.005; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability (3 minutes) 102.2 % - Dermal - In Vitro; SkinEthic Corrosion sheet=Data_invitro; excel_row=1314; Record_ID=skin_irritation_invitro_2338; Data_Type=In Vitro; Concentration=20; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=SkinEthic Corrosion; Endpoint=Viability (3 minutes); Response=102.2; Response_Unit=%; Reference=Tornier et al. 2010; 20471469; 10.1016/j.tiv.2010.05.005; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability (3 minutes) 104.9 % - Dermal - In Vitro; EpiSkin Corrosion sheet=Data_invitro; excel_row=1316; Record_ID=skin_irritation_invitro_2368; Data_Type=In Vitro; Concentration=20; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=EpiSkin Corrosion; Endpoint=Viability (3 minutes); Response=104.9; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability (3 minutes) 109.1 % - Dermal - In Vitro; LabCyte Corrosion sheet=Data_invitro; excel_row=1313; Record_ID=skin_irritation_invitro_2315; Data_Type=In Vitro; Concentration=20; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte Corrosion; Endpoint=Viability (3 minutes); Response=109.1; Response_Unit=%; Reference=Katoh et al. 2010; 20519850; 10.2131/jts.35.411; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability (3 minutes) 114 % - Dermal - In Vitro; EpiSkin Corrosion sheet=Data_invitro; excel_row=1317; Record_ID=skin_irritation_invitro_2370; Data_Type=In Vitro; Concentration=20; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=EpiSkin Corrosion; Endpoint=Viability (3 minutes); Response=114; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability (42 hours) 0.9 % - Dermal - In Vitro; Vitrolife-Skin Irritation sheet=Data_invitro; excel_row=1258; Record_ID=skin_irritation_invitro_761; Data_Type=In Vitro; Concentration=50; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=Vitrolife-Skin Irritation; Endpoint=Viability (42 hours); Response=0.9; Response_Unit=%; Reference=Morikawa et al. 2008; Not available; 10.11232/AATEX.13.11; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability (42 hours) 1.6 % - Dermal - In Vitro; Vitrolife-Skin Irritation sheet=Data_invitro; excel_row=1254; Record_ID=skin_irritation_invitro_760; Data_Type=In Vitro; Concentration=20; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=Vitrolife-Skin Irritation; Endpoint=Viability (42 hours); Response=1.6; Response_Unit=%; Reference=Morikawa et al. 2008; Not available; 10.11232/AATEX.13.11; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability (60 minutes) 20.2 % - Dermal - In Vitro; EpiDerm Corrosion sheet=Data_invitro; excel_row=1343; Record_ID=skin_irritation_invitro_2362; Data_Type=In Vitro; Concentration=20; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=EpiDerm Corrosion; Endpoint=Viability (60 minutes); Response=20.2; Response_Unit=%; Reference=Liebsch et al. 2000; 25419920; 10.1177/026119290002800309; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability (60 minutes) 23.3 % - Dermal - In Vitro; EpiDerm Corrosion sheet=Data_invitro; excel_row=1336; Record_ID=skin_irritation_invitro_2358; Data_Type=In Vitro; Concentration=20; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=EpiDerm Corrosion; Endpoint=Viability (60 minutes); Response=23.3; Response_Unit=%; Reference=Liebsch et al. 2000; 25419920; 10.1177/026119290002800309; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability (60 minutes) 24.8 % - Dermal - In Vitro; EpiDerm Corrosion sheet=Data_invitro; excel_row=1339; Record_ID=skin_irritation_invitro_2366; Data_Type=In Vitro; Concentration=20; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=EpiDerm Corrosion; Endpoint=Viability (60 minutes); Response=24.8; Response_Unit=%; Reference=Liebsch et al. 2000; 25419920; 10.1177/026119290002800309; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability (60 minutes) 27.6 % - Dermal - In Vitro; EpiDerm Corrosion sheet=Data_invitro; excel_row=1337; Record_ID=skin_irritation_invitro_2360; Data_Type=In Vitro; Concentration=20; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=EpiDerm Corrosion; Endpoint=Viability (60 minutes); Response=27.6; Response_Unit=%; Reference=Liebsch et al. 2000; 25419920; 10.1177/026119290002800309; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability (60 minutes) 28.6 % - Dermal - In Vitro; LabCyte Corrosion sheet=Data_invitro; excel_row=1324; Record_ID=skin_irritation_invitro_2315; Data_Type=In Vitro; Concentration=20; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LabCyte Corrosion; Endpoint=Viability (60 minutes); Response=28.6; Response_Unit=%; Reference=Katoh et al. 2010; 20519850; 10.2131/jts.35.411; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability (60 minutes) 33.2 % - Dermal - In Vitro; EpiDerm Corrosion sheet=Data_invitro; excel_row=1338; Record_ID=skin_irritation_invitro_2364; Data_Type=In Vitro; Concentration=20; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=EpiDerm Corrosion; Endpoint=Viability (60 minutes); Response=33.20; Response_Unit=%; Reference=Liebsch et al. 2000; 25419920; 10.1177/026119290002800309; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability (60 minutes) 34.3 % - Dermal - In Vitro; SkinEthic Corrosion sheet=Data_invitro; excel_row=1334; Record_ID=skin_irritation_invitro_2338; Data_Type=In Vitro; Concentration=20; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=SkinEthic Corrosion; Endpoint=Viability (60 minutes); Response=34.30; Response_Unit=%; Reference=Tornier et al. 2010; 20471469; 10.1016/j.tiv.2010.05.005; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability (60 minutes) 85.1 % - Dermal - In Vitro; SkinEthic Corrosion sheet=Data_invitro; excel_row=1333; Record_ID=skin_irritation_invitro_2336; Data_Type=In Vitro; Concentration=20; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=SkinEthic Corrosion; Endpoint=Viability (60 minutes); Response=85.1; Response_Unit=%; Reference=Tornier et al. 2010; 20471469; 10.1016/j.tiv.2010.05.005; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability (60 minutes) 90.2 % - Dermal - In Vitro; EpiSkin Corrosion sheet=Data_invitro; excel_row=1342; Record_ID=skin_irritation_invitro_2372; Data_Type=In Vitro; Concentration=20; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=EpiSkin Corrosion; Endpoint=Viability (60 minutes); Response=90.2; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability (60 minutes) 92.6 % - Dermal - In Vitro; SkinEthic Corrosion sheet=Data_invitro; excel_row=1323; Record_ID=skin_irritation_invitro_2313; Data_Type=In Vitro; Concentration=20; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=SkinEthic Corrosion; Endpoint=Viability (60 minutes); Response=92.6; Response_Unit=%; Reference=Kandarova et al. 2006; 16455230; 10.1016/j.tiv.2005.11.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability (60 minutes) 100.1 % - Dermal - In Vitro; EpiSkin Corrosion sheet=Data_invitro; excel_row=1340; Record_ID=skin_irritation_invitro_2368; Data_Type=In Vitro; Concentration=20; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=EpiSkin Corrosion; Endpoint=Viability (60 minutes); Response=100.1; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability (60 minutes) 103 % - Dermal - In Vitro; SkinEthic Corrosion sheet=Data_invitro; excel_row=1325; Record_ID=skin_irritation_invitro_2334; Data_Type=In Vitro; Concentration=20; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=SkinEthic Corrosion; Endpoint=Viability (60 minutes); Response=103; Response_Unit=%; Reference=Tornier et al. 2010; 20471469; 10.1016/j.tiv.2010.05.005; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin irritation Viability (60 minutes) 114.6 % - Dermal - In Vitro; EpiSkin Corrosion sheet=Data_invitro; excel_row=1341; Record_ID=skin_irritation_invitro_2370; Data_Type=In Vitro; Concentration=20; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=EpiSkin Corrosion; Endpoint=Viability (60 minutes); Response=114.6; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization 92 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
NTP ICE skin sensitization CD86, EC150 44.37 ug/mL - Dermal - In Vitro; hCLAT2015; h-CLAT sheet=Data_invitro; excel_row=3270; Record_ID=skin_sensitization_invitro_759; Data_Type=In Vitro; Internal_Data_Source=hCLAT2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=h-CLAT; Endpoint=CD86, EC150; Reported_Response=44.37; Reported_Response_Unit=ug/mL; Response=44.37; Response_Unit=ug/mL; Reference=Sakaguchi et al. 2010; 20510347; 10.1016/j.tiv.2010.05.012|h-CLAT RingTrial EC values for NICEATM (undated); URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization CD86, EC150 54.61 ug/mL - Dermal - In Vitro; CE_USENSE2018; U-SENS sheet=Data_invitro; excel_row=8488; Record_ID=skin_sensitization_invitro_2338; Data_Type=In Vitro; Internal_Data_Source=CE_USENSE2018; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=U-SENS; Endpoint=CD86, EC150; Reported_Response=54.61; Reported_Response_Unit=ug/mL; Response=54.61; Response_Unit=ug/mL; Reference=Piroird et al. 2015; 25820135; 10.1016/j.tiv.2015.03.009; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization CD86, EC150 >2018.66 ug/mL - Dermal - In Vitro; Urbisch_SkinSensitization2020; U-SENS sheet=Data_invitro; excel_row=8225; Record_ID=skin_sensitization_invitro_2248; Data_Type=In Vitro; Internal_Data_Source=Urbisch_SkinSensitization2020; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=U-SENS; Endpoint=CD86, EC150; Response_Modifier=>; Reported_Response_Modifier=>; Reported_Response=7000; Reported_Response_Unit=uM; Conversion_Factor_Value=288.38; Conversion_Factor_Source=EPA Dashboard; Converted_Response_Modifier=>; Converted_Response=2018.66; Converted_Response_Unit=ug/mL; Response=2018.66; Response_Unit=ug/mL; Reference=Urbisch et al. 2015; 25541156; 10.1016/j.yrtph.2014.12.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization CV70 75.54 ug/mL - Dermal - In Vitro; CE_USENSE2018; U-SENS sheet=Data_invitro; excel_row=8489; Record_ID=skin_sensitization_invitro_2338; Data_Type=In Vitro; Internal_Data_Source=CE_USENSE2018; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=U-SENS; Endpoint=CV70; Reported_Response=75.54; Reported_Response_Unit=ug/mL; Response=75.54; Response_Unit=ug/mL; Reference=Piroird et al. 2015; 25820135; 10.1016/j.tiv.2015.03.009; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization CV75 27.8 ug/mL - Dermal - In Vitro; hCLAT2015; h-CLAT sheet=Data_invitro; excel_row=3302; Record_ID=skin_sensitization_invitro_766; Data_Type=In Vitro; Internal_Data_Source=hCLAT2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=h-CLAT; Endpoint=CV75; Reported_Response=27.8; Reported_Response_Unit=ug/mL; Response=27.8; Response_Unit=ug/mL; Reference=Bauch et al. 2011; 21669280; 10.1016/j.tiv.2011.05.030|Bauch et al. 2012; 22659254; 10.1016/j.yrtph.2012.05.013; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization CV75 60 ug/mL - Dermal - In Vitro; CE_hCLAT2018; h-CLAT sheet=Data_invitro; excel_row=2276; Record_ID=skin_sensitization_invitro_557; Data_Type=In Vitro; Internal_Data_Source=CE_hCLAT2018; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=h-CLAT; Endpoint=CV75; Reported_Response=60; Reported_Response_Unit=ug/mL; Response=60; Response_Unit=ug/mL; Reference=Urbisch et al. 2015; 25541156; 10.1016/j.yrtph.2014.12.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization CV75 60.9 ug/mL - Dermal - In Vitro; hCLAT2015; h-CLAT sheet=Data_invitro; excel_row=3296; Record_ID=skin_sensitization_invitro_764; Data_Type=In Vitro; Internal_Data_Source=hCLAT2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=h-CLAT; Endpoint=CV75; Reported_Response=60.9; Reported_Response_Unit=ug/mL; Response=60.9; Response_Unit=ug/mL; Reference=Sakaguchi et al. 2010; 20510347; 10.1016/j.tiv.2010.05.012|h-CLAT RingTrial EC values for NICEATM (undated); URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization CV75 61.7 ug/mL - Dermal - In Vitro; hCLAT2015; h-CLAT sheet=Data_invitro; excel_row=3288; Record_ID=skin_sensitization_invitro_763; Data_Type=In Vitro; Internal_Data_Source=hCLAT2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=h-CLAT; Endpoint=CV75; Reported_Response=61.7; Reported_Response_Unit=ug/mL; Response=61.7; Response_Unit=ug/mL; Reference=Sakaguchi et al. 2010; 20510347; 10.1016/j.tiv.2010.05.012|h-CLAT RingTrial EC values for NICEATM (undated); URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization CV75 62 ug/mL - Dermal - In Vitro; hCLAT2015; h-CLAT sheet=Data_invitro; excel_row=3280; Record_ID=skin_sensitization_invitro_762; Data_Type=In Vitro; Internal_Data_Source=hCLAT2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=h-CLAT; Endpoint=CV75; Reported_Response=62; Reported_Response_Unit=ug/mL; Response=62; Response_Unit=ug/mL; Reference=Sakaguchi et al. 2010; 20510347; 10.1016/j.tiv.2010.05.012|h-CLAT RingTrial EC values for NICEATM (undated); URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization CV75 69.5 ug/mL - Dermal - In Vitro; hCLAT2015; h-CLAT sheet=Data_invitro; excel_row=3263; Record_ID=skin_sensitization_invitro_758; Data_Type=In Vitro; Internal_Data_Source=hCLAT2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=h-CLAT; Endpoint=CV75; Reported_Response=69.5; Reported_Response_Unit=ug/mL; Response=69.5; Response_Unit=ug/mL; Reference=Sakaguchi et al. 2010; 20510347; 10.1016/j.tiv.2010.05.012|h-CLAT RingTrial EC values for NICEATM (undated); URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization Depletion Cys -0.1 % - Dermal - In Vitro; DPRA2015; DPRA sheet=Data_invitro; excel_row=1128; Record_ID=skin_sensitization_invitro_306; Data_Type=In Vitro; Internal_Data_Source=DPRA2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=DPRA; Endpoint=Depletion Cys; Reported_Response=-0.1; Reported_Response_Unit=%; Response=-0.1; Response_Unit=%; Reference=Bauch et al. 2011; 21669280; 10.1016/j.tiv.2011.05.030|Bauch et al. 2012; 22659254; 10.1016/j.yrtph.2012.05.013; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization Depletion Lys 0 % - Dermal - In Vitro; DPRA2015; DPRA sheet=Data_invitro; excel_row=1134; Record_ID=skin_sensitization_invitro_308; Data_Type=In Vitro; Internal_Data_Source=DPRA2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=DPRA; Endpoint=Depletion Lys; Reported_Response=0; Reported_Response_Unit=%; Response=0; Response_Unit=%; Reference=Natsch et al. 2013; 23576290; 10.1002/jat.2868; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization Depletion Lys 97.1 % - Dermal - In Vitro; DPRA2015; DPRA sheet=Data_invitro; excel_row=1126; Record_ID=skin_sensitization_invitro_306; Data_Type=In Vitro; Internal_Data_Source=DPRA2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=DPRA; Endpoint=Depletion Lys; Reported_Response=97.1; Reported_Response_Unit=%; Response=97.1; Response_Unit=%; Reference=Bauch et al. 2011; 21669280; 10.1016/j.tiv.2011.05.030|Bauch et al. 2012; 22659254; 10.1016/j.yrtph.2012.05.013; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization Depletion Lys + Cys 48.5 % - Dermal - In Vitro; DPRA2015; DPRA sheet=Data_invitro; excel_row=1130; Record_ID=skin_sensitization_invitro_306; Data_Type=In Vitro; Internal_Data_Source=DPRA2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=DPRA; Endpoint=Depletion Lys + Cys; Reported_Response=48.5; Reported_Response_Unit=%; Response=48.5; Response_Unit=%; Reference=Bauch et al. 2011; 21669280; 10.1016/j.tiv.2011.05.030|Bauch et al. 2012; 22659254; 10.1016/j.yrtph.2012.05.013; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization EC1.5 >30 uM - Dermal - In Vitro; Urbisch_SkinSensitization2020; LuSens sheet=Data_invitro; excel_row=7588; Record_ID=skin_sensitization_invitro_1829; Data_Type=In Vitro; Internal_Data_Source=Urbisch_SkinSensitization2020; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LuSens; Endpoint=EC1.5; Response_Modifier=>; Reported_Response_Modifier=>; Reported_Response=30; Reported_Response_Unit=uM; Response=30; Response_Unit=uM; Reference=Urbisch et al. 2015; 25541156; 10.1016/j.yrtph.2014.12.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization EC1.5 32.78 uM - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5261; Record_ID=skin_sensitization_invitro_1226; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=EC1.5; Reported_Response=32.78; Reported_Response_Unit=uM; Response=32.78; Response_Unit=uM; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization EC1.5 33.75 uM - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5262; Record_ID=skin_sensitization_invitro_1234; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=EC1.5; Reported_Response=33.75; Reported_Response_Unit=uM; Response=33.75; Response_Unit=uM; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization EC1.5 33.8 uM - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5263; Record_ID=skin_sensitization_invitro_1231; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=EC1.5; Reported_Response=33.799999999999997; Reported_Response_Unit=uM; Response=33.8; Response_Unit=uM; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization EC1.5 33.9 uM - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5264; Record_ID=skin_sensitization_invitro_1228; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=EC1.5; Reported_Response=33.9; Reported_Response_Unit=uM; Response=33.9; Response_Unit=uM; Reference=Natsch et al. 2011; 22023385; 10.1021/tx2003678; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization EC1.5 34.26 uM - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5265; Record_ID=skin_sensitization_invitro_1225; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=EC1.5; Reported_Response=34.26; Reported_Response_Unit=uM; Response=34.26; Response_Unit=uM; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization EC1.5 34.3 uM - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5266; Record_ID=skin_sensitization_invitro_1229; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=EC1.5; Reported_Response=34.299999999999997; Reported_Response_Unit=uM; Response=34.3; Response_Unit=uM; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization EC1.5 34.69 uM - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5267; Record_ID=skin_sensitization_invitro_1224; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=EC1.5; Reported_Response=34.69; Reported_Response_Unit=uM; Response=34.69; Response_Unit=uM; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization EC1.5 35.3 uM - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5268; Record_ID=skin_sensitization_invitro_1227; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=EC1.5; Reported_Response=35.299999999999997; Reported_Response_Unit=uM; Response=35.3; Response_Unit=uM; Reference=Natsch et al. 2011; 22023385; 10.1021/tx2003678; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization EC1.5 35.4 uM - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5269; Record_ID=skin_sensitization_invitro_1223; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=EC1.5; Reported_Response=35.4; Reported_Response_Unit=uM; Response=35.4; Response_Unit=uM; Reference=Ball et al. 2011; 21645576; 10.1016/j.yrtph.2011.05.007; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization EC1.5 37.85 uM - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5270; Record_ID=skin_sensitization_invitro_1236; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=EC1.5; Reported_Response=37.85; Reported_Response_Unit=uM; Response=37.85; Response_Unit=uM; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization EC1.5 37.9 uM - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5271; Record_ID=skin_sensitization_invitro_1230; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=EC1.5; Reported_Response=37.9; Reported_Response_Unit=uM; Response=37.9; Response_Unit=uM; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization EC1.5 47.5 uM - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5272; Record_ID=skin_sensitization_invitro_1245; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=EC1.5; Reported_Response=47.5; Reported_Response_Unit=uM; Response=47.5; Response_Unit=uM; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization EC1.5 >2000 uM - Dermal - In Vitro; CE_KeratinoSense2018; KeratinoSens sheet=Data_invitro; excel_row=5260; Record_ID=skin_sensitization_invitro_1247; Data_Type=In Vitro; Internal_Data_Source=CE_KeratinoSense2018; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=EC1.5; Response_Modifier=>; Reported_Response_Modifier=>; Reported_Response=2000; Reported_Response_Unit=uM; Response=2000; Response_Unit=uM; Reference=Emter et al. 2010; 20307559; 10.1016/j.taap.2010.03.009|Natsch et al. 2013; 23576290; 10.1002/jat.2868; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization EC3 1.5 % Mouse Dermal - In Vivo; LLNAdb2013; LLNA sheet=Data_invivo; excel_row=13596; Record_ID=skin_sensitization_invivo_3823; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LLNA; Endpoint=EC3; Response=1.5; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Loveless et al. 1996; 8644112; 10.1016/0300-483x(95)03279-o; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization EC3 1.7 % Mouse Dermal - In Vivo; LLNAdb2013; LLNA sheet=Data_invivo; excel_row=13603; Record_ID=skin_sensitization_invivo_3831; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LLNA; Endpoint=EC3; Response=1.7; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Montelius et al. 1994; Not available; Not available; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization EC3 2.5 % Mouse Dermal - In Vivo; LLNAdb2013; LLNA sheet=Data_invivo; excel_row=13607; Record_ID=skin_sensitization_invivo_3839; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LLNA; Endpoint=EC3; Response=2.5; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Basketter et al. 1994; 8045461; 10.1016/0278-6915(94)90112-0; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization EC3 3.09 % Mouse Dermal - In Vivo; LLNAdb2013; LLNA sheet=Data_invivo; excel_row=13606; Record_ID=skin_sensitization_invivo_3837; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LLNA; Endpoint=EC3; Response=3.09; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Basketter et al. 1994; 8045461; 10.1016/0278-6915(94)90112-0; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization EC3 4 % Mouse Dermal - In Vivo; LLNAdb2013; LLNA sheet=Data_invivo; excel_row=13600; Record_ID=skin_sensitization_invivo_3827; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LLNA; Endpoint=EC3; Response=4; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Loveless et al. 1996; 8644112; 10.1016/0300-483x(95)03279-o; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization EC3 4.4 % Mouse Dermal - In Vivo; LLNAdb2013; LLNA sheet=Data_invivo; excel_row=13618; Record_ID=skin_sensitization_invivo_3821; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LLNA; Endpoint=EC3; Response=4.4; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Loveless et al. 1996; 8644112; 10.1016/0300-483x(95)03279-o; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization EC3 4.9 % Mouse Dermal - In Vivo; LLNAdb2013; LLNA sheet=Data_invivo; excel_row=13604; Record_ID=skin_sensitization_invivo_3834; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LLNA; Endpoint=EC3; Response=4.9; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=BASF personal communication (undated); URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization EC3 8.1 % Mouse Dermal - In Vivo; LLNA2013; LLNA sheet=Data_invivo; excel_row=12868; Record_ID=skin_sensitization_invivo_491; Data_Type=In Vivo; Internal_Data_Source=LLNA2013; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LLNA; Endpoint=EC3; Response=8.1; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=ICCVAM 2009; Not available; https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-ps/llnaperfstds.pdf; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization EC3 13.4 % Mouse Dermal - In Vivo; LLNAdb2013; LLNA sheet=Data_invivo; excel_row=13616; Record_ID=skin_sensitization_invivo_3852; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LLNA; Endpoint=EC3; Response=13.4; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Gerberick et al. 2005; 16536334; Not available; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization EC3 14 % Mouse Dermal - In Vivo; Urbisch_SkinSensitization2020; LLNA sheet=Data_invivo; excel_row=12925; Record_ID=skin_sensitization_invivo_2855; Data_Type=In Vivo; Internal_Data_Source=Urbisch_SkinSensitization2020; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LLNA; Endpoint=EC3; Response=14; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Urbisch et al. 2015; 25541156; 10.1016/j.yrtph.2014.12.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization EC3 17.1 % Mouse Dermal - In Vivo; LLNAdb2013; LLNA sheet=Data_invivo; excel_row=13598; Record_ID=skin_sensitization_invivo_3825; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LLNA; Endpoint=EC3; Response=17.1; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Loveless et al. 1996; 8644112; 10.1016/0300-483x(95)03279-o; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization IC50 29.9 uM - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5286; Record_ID=skin_sensitization_invitro_1243; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=IC50; Reported_Response=29.9; Reported_Response_Unit=uM; Response=29.9; Response_Unit=uM; Reference=Bauch et al. 2011; 21669280; 10.1016/j.tiv.2011.05.030|Bauch et al. 2012; 22659254; 10.1016/j.yrtph.2012.05.013; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization IC50 >36 uM - Dermal - In Vitro; Urbisch_SkinSensitization2020; LuSens sheet=Data_invitro; excel_row=7660; Record_ID=skin_sensitization_invitro_1829; Data_Type=In Vitro; Internal_Data_Source=Urbisch_SkinSensitization2020; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LuSens; Endpoint=IC50; Response_Modifier=>; Reported_Response_Modifier=>; Reported_Response=36; Reported_Response_Unit=uM; Response=36; Response_Unit=uM; Reference=Urbisch et al. 2015; 25541156; 10.1016/j.yrtph.2014.12.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization IC50 43.03 uM - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5287; Record_ID=skin_sensitization_invitro_1246; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=IC50; Reported_Response=43.03; Reported_Response_Unit=uM; Response=43.03; Response_Unit=uM; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization IC50 44.42 uM - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5288; Record_ID=skin_sensitization_invitro_1234; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=IC50; Reported_Response=44.42; Reported_Response_Unit=uM; Response=44.42; Response_Unit=uM; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization IC50 44.7 uM - Dermal - In Vitro; CE_KeratinoSense2018; KeratinoSens sheet=Data_invitro; excel_row=5289; Record_ID=skin_sensitization_invitro_1247; Data_Type=In Vitro; Internal_Data_Source=CE_KeratinoSense2018; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=IC50; Reported_Response=44.7; Reported_Response_Unit=uM; Response=44.7; Response_Unit=uM; Reference=Emter et al. 2010; 20307559; 10.1016/j.taap.2010.03.009|Natsch et al. 2013; 23576290; 10.1002/jat.2868; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization IC50 45.11 uM - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5290; Record_ID=skin_sensitization_invitro_1238; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=IC50; Reported_Response=45.11; Reported_Response_Unit=uM; Response=45.11; Response_Unit=uM; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization IC50 45.41 uM - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5291; Record_ID=skin_sensitization_invitro_1236; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=IC50; Reported_Response=45.41; Reported_Response_Unit=uM; Response=45.41; Response_Unit=uM; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization IC50 46.2 uM - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5292; Record_ID=skin_sensitization_invitro_1242; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=IC50; Reported_Response=46.2; Reported_Response_Unit=uM; Response=46.2; Response_Unit=uM; Reference=Natsch et al. 2011; 22023385; 10.1021/tx2003678; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization IC50 48.29 uM - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5293; Record_ID=skin_sensitization_invitro_1237; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=IC50; Reported_Response=48.29; Reported_Response_Unit=uM; Response=48.29; Response_Unit=uM; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization IC50 51.4 uM - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5294; Record_ID=skin_sensitization_invitro_1230; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=IC50; Reported_Response=51.4; Reported_Response_Unit=uM; Response=51.4; Response_Unit=uM; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization IC50 54.5 uM - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5295; Record_ID=skin_sensitization_invitro_1241; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=IC50; Reported_Response=54.5; Reported_Response_Unit=uM; Response=54.5; Response_Unit=uM; Reference=Natsch et al. 2011; 22023385; 10.1021/tx2003678; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization IC50 55.23 uM - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5296; Record_ID=skin_sensitization_invitro_1245; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=IC50; Reported_Response=55.23; Reported_Response_Unit=uM; Response=55.23; Response_Unit=uM; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization IC50 57 uM - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5297; Record_ID=skin_sensitization_invitro_1227; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=IC50; Reported_Response=57; Reported_Response_Unit=uM; Response=57; Response_Unit=uM; Reference=Natsch et al. 2011; 22023385; 10.1021/tx2003678; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization IC50 57.75 uM - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5298; Record_ID=skin_sensitization_invitro_1231; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=IC50; Reported_Response=57.75; Reported_Response_Unit=uM; Response=57.75; Response_Unit=uM; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization IC50 62.47 uM - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5299; Record_ID=skin_sensitization_invitro_1229; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=IC50; Reported_Response=62.47; Reported_Response_Unit=uM; Response=62.47; Response_Unit=uM; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization IC50 74.5 uM - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5300; Record_ID=skin_sensitization_invitro_1240; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=IC50; Reported_Response=74.5; Reported_Response_Unit=uM; Response=74.5; Response_Unit=uM; Reference=Natsch et al. 2011; 22023385; 10.1021/tx2003678; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization IC50 84.57 uM - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5301; Record_ID=skin_sensitization_invitro_1235; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=IC50; Reported_Response=84.57; Reported_Response_Unit=uM; Response=84.57; Response_Unit=uM; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization IC50 84.88 uM - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5302; Record_ID=skin_sensitization_invitro_1232; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=IC50; Reported_Response=84.88; Reported_Response_Unit=uM; Response=84.88; Response_Unit=uM; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization IC50 86.83 uM - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5303; Record_ID=skin_sensitization_invitro_1225; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=IC50; Reported_Response=86.83; Reported_Response_Unit=uM; Response=86.83; Response_Unit=uM; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization IC50 88.18 uM - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5304; Record_ID=skin_sensitization_invitro_1233; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=IC50; Reported_Response=88.18; Reported_Response_Unit=uM; Response=88.18; Response_Unit=uM; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization IC50 90.72 uM - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5305; Record_ID=skin_sensitization_invitro_1224; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=IC50; Reported_Response=90.72; Reported_Response_Unit=uM; Response=90.72; Response_Unit=uM; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization IC50 91.1 uM - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5306; Record_ID=skin_sensitization_invitro_1228; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=IC50; Reported_Response=91.1; Reported_Response_Unit=uM; Response=91.1; Response_Unit=uM; Reference=Natsch et al. 2011; 22023385; 10.1021/tx2003678; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization IC50 96.08 uM - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5307; Record_ID=skin_sensitization_invitro_1226; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=IC50; Reported_Response=96.08; Reported_Response_Unit=uM; Response=96.08; Response_Unit=uM; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization Imax 0.7736 ratio - Dermal - In Vitro; Urbisch_SkinSensitization2020; LuSens sheet=Data_invitro; excel_row=7563; Record_ID=skin_sensitization_invitro_1829; Data_Type=In Vitro; Internal_Data_Source=Urbisch_SkinSensitization2020; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LuSens; Endpoint=Imax; Reported_Response=0.773627149; Reported_Response_Unit=Unitless; Response=0.7736; Response_Unit=Ratio; Reference=Urbisch et al. 2015; 25541156; 10.1016/j.yrtph.2014.12.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization Imax 1.092 ratio - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5308; Record_ID=skin_sensitization_invitro_1232; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=Imax; Reported_Response=1.0920000000000001; Reported_Response_Unit=Unitless; Response=1.092; Response_Unit=Ratio; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization Imax 1.111 ratio - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5309; Record_ID=skin_sensitization_invitro_1244; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=Imax; Reported_Response=1.111; Reported_Response_Unit=Unitless; Response=1.111; Response_Unit=Ratio; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization Imax 1.16 ratio - Dermal - In Vitro; CE_KeratinoSense2018; KeratinoSens sheet=Data_invitro; excel_row=5310; Record_ID=skin_sensitization_invitro_1247; Data_Type=In Vitro; Internal_Data_Source=CE_KeratinoSense2018; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=Imax; Reported_Response=1.1599999999999999; Reported_Response_Unit=Unitless; Response=1.16; Response_Unit=Ratio; Reference=Emter et al. 2010; 20307559; 10.1016/j.taap.2010.03.009|Natsch et al. 2013; 23576290; 10.1002/jat.2868; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization Imax 1.199 ratio - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5311; Record_ID=skin_sensitization_invitro_1246; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=Imax; Reported_Response=1.1990000000000001; Reported_Response_Unit=Unitless; Response=1.199; Response_Unit=Ratio; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization Imax 1.212 ratio - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5312; Record_ID=skin_sensitization_invitro_1239; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=Imax; Reported_Response=1.212; Reported_Response_Unit=Unitless; Response=1.212; Response_Unit=Ratio; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization Imax 1.309 ratio - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5313; Record_ID=skin_sensitization_invitro_1233; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=Imax; Reported_Response=1.3089999999999999; Reported_Response_Unit=Unitless; Response=1.309; Response_Unit=Ratio; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization Imax 1.4 ratio - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5314; Record_ID=skin_sensitization_invitro_1240; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=Imax; Reported_Response=1.4; Reported_Response_Unit=Unitless; Response=1.4; Response_Unit=Ratio; Reference=Natsch et al. 2011; 22023385; 10.1021/tx2003678; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization Imax 1.793 ratio - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5315; Record_ID=skin_sensitization_invitro_1238; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=Imax; Reported_Response=1.7929999999999999; Reported_Response_Unit=Unitless; Response=1.793; Response_Unit=Ratio; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization Imax 1.915 ratio - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5316; Record_ID=skin_sensitization_invitro_1245; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=Imax; Reported_Response=1.915; Reported_Response_Unit=Unitless; Response=1.915; Response_Unit=Ratio; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization Imax 2.617 ratio - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5318; Record_ID=skin_sensitization_invitro_1237; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=Imax; Reported_Response=2.617; Reported_Response_Unit=Unitless; Response=2.617; Response_Unit=Ratio; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization Imax 2.7 ratio - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5319; Record_ID=skin_sensitization_invitro_1242; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=Imax; Reported_Response=2.7; Reported_Response_Unit=Unitless; Response=2.7; Response_Unit=Ratio; Reference=Natsch et al. 2011; 22023385; 10.1021/tx2003678; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization Imax 3.575 ratio - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5320; Record_ID=skin_sensitization_invitro_1236; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=Imax; Reported_Response=3.5750000000000002; Reported_Response_Unit=Unitless; Response=3.575; Response_Unit=Ratio; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization Imax 3.748 ratio - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5321; Record_ID=skin_sensitization_invitro_1230; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=Imax; Reported_Response=3.7480000000000002; Reported_Response_Unit=Unitless; Response=3.748; Response_Unit=Ratio; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization Imax 4 ratio - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5322; Record_ID=skin_sensitization_invitro_1223; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=Imax; Reported_Response=4; Reported_Response_Unit=Unitless; Response=4; Response_Unit=Ratio; Reference=Ball et al. 2011; 21645576; 10.1016/j.yrtph.2011.05.007; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization Imax 4.526 ratio - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5323; Record_ID=skin_sensitization_invitro_1235; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=Imax; Reported_Response=4.5259999999999998; Reported_Response_Unit=Unitless; Response=4.526; Response_Unit=Ratio; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization Imax 4.588 ratio - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5324; Record_ID=skin_sensitization_invitro_1224; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=Imax; Reported_Response=4.5880000000000001; Reported_Response_Unit=Unitless; Response=4.588; Response_Unit=Ratio; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization Imax 4.77 ratio - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5325; Record_ID=skin_sensitization_invitro_1243; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=Imax; Reported_Response=4.7699999999999996; Reported_Response_Unit=Unitless; Response=4.77; Response_Unit=Ratio; Reference=Bauch et al. 2011; 21669280; 10.1016/j.tiv.2011.05.030|Bauch et al. 2012; 22659254; 10.1016/j.yrtph.2012.05.013; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization Imax 5.1 ratio - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5326; Record_ID=skin_sensitization_invitro_1241; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=Imax; Reported_Response=5.0999999999999996; Reported_Response_Unit=Unitless; Response=5.1; Response_Unit=Ratio; Reference=Natsch et al. 2011; 22023385; 10.1021/tx2003678; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization Imax 5.9 ratio - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5327; Record_ID=skin_sensitization_invitro_1227; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=Imax; Reported_Response=5.9; Reported_Response_Unit=Unitless; Response=5.9; Response_Unit=Ratio; Reference=Natsch et al. 2011; 22023385; 10.1021/tx2003678; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization Imax 6.344 ratio - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5328; Record_ID=skin_sensitization_invitro_1229; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=Imax; Reported_Response=6.3440000000000003; Reported_Response_Unit=Unitless; Response=6.344; Response_Unit=Ratio; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization Imax 6.726 ratio - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5329; Record_ID=skin_sensitization_invitro_1225; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=Imax; Reported_Response=6.726; Reported_Response_Unit=Unitless; Response=6.726; Response_Unit=Ratio; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization Imax 7.736 ratio - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5330; Record_ID=skin_sensitization_invitro_1231; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=Imax; Reported_Response=7.7359999999999998; Reported_Response_Unit=Unitless; Response=7.736; Response_Unit=Ratio; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization Imax 8.1 ratio - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5331; Record_ID=skin_sensitization_invitro_1228; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=Imax; Reported_Response=8.1; Reported_Response_Unit=Unitless; Response=8.1; Response_Unit=Ratio; Reference=Natsch et al. 2011; 22023385; 10.1021/tx2003678; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization Imax 9.681 ratio - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5332; Record_ID=skin_sensitization_invitro_1234; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=Imax; Reported_Response=9.6809999999999992; Reported_Response_Unit=Unitless; Response=9.681; Response_Unit=Ratio; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization Imax 13.13 ratio - Dermal - In Vitro; KeratinoSens2015; KeratinoSens sheet=Data_invitro; excel_row=5317; Record_ID=skin_sensitization_invitro_1226; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=KeratinoSens; Endpoint=Imax; Reported_Response=13.132999999999999; Reported_Response_Unit=Unitless; Response=13.13; Response_Unit=Ratio; Reference=Joint Research Centre of the European Union 2014; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization Incidence of positive responses 0 % Human Dermal - In Vivo; HPPT2020WIP; Human Maximization Test sheet=Data_invivo; excel_row=5699; Record_ID=skin_sensitization_invivo_1317; Data_Type=In Vivo; Internal_Data_Source=HPPT2020WIP; Concentration=10.0; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=Human Maximization Test; Endpoint=Incidence of positive responses; Response=0; Response_Unit=%; Species=Human; Route=Dermal; Reference=Kligman 1966; 5924294; 10.1038/jid.1966.160|Magnusson and Kligman 1969; 5774356; 10.1038/jid.1969.42|Basketter et al. 1994; 8045461; 10.1016/0278-6915(94)90112-0|Basketter et al. 1999; 10654593; 10.1016/S0278-6915(99)00112-x|Gerberick et al. 2000; 10684384; 10.1053/ajcd.2000.0003|ICCVAM 2009; Not available; https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-ps/llnaperfstds.pdf|Basketter et al. 2014; 24407057; 10.1097/der.0000000000000003; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization Induction dose per skin area 6207 ug/cm2 Human Dermal - In Vivo; HPPT2020WIP; Human Maximization Test sheet=Data_invivo; excel_row=5696; Record_ID=skin_sensitization_invivo_1317; Data_Type=In Vivo; Internal_Data_Source=HPPT2020WIP; Concentration=10.0; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=Human Maximization Test; Endpoint=Induction dose per skin area; Response=6207; Response_Unit=ug/cm2; Species=Human; Route=Dermal; Reference=Kligman 1966; 5924294; 10.1038/jid.1966.160|Magnusson and Kligman 1969; 5774356; 10.1038/jid.1969.42|Basketter et al. 1994; 8045461; 10.1016/0278-6915(94)90112-0|Basketter et al. 1999; 10654593; 10.1016/S0278-6915(99)00112-x|Gerberick et al. 2000; 10684384; 10.1053/ajcd.2000.0003|ICCVAM 2009; Not available; https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-ps/llnaperfstds.pdf|Basketter et al. 2014; 24407057; 10.1097/der.0000000000000003; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization Max stimulation index 8.9 ratio Mouse Dermal - In Vivo; LLNA2013; LLNA sheet=Data_invivo; excel_row=12867; Record_ID=skin_sensitization_invivo_491; Data_Type=In Vivo; Internal_Data_Source=LLNA2013; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=LLNA; Endpoint=Max stimulation index; Response=8.9; Response_Unit=Ratio; Species=Mouse; Route=Dermal; Reference=ICCVAM 2009; Not available; https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-ps/llnaperfstds.pdf; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
NTP ICE skin sensitization Relative reliability score 1 unitless Human Dermal - In Vivo; HPPT2020WIP; Human Maximization Test sheet=Data_invivo; excel_row=5703; Record_ID=skin_sensitization_invivo_1317; Data_Type=In Vivo; Internal_Data_Source=HPPT2020WIP; Concentration=10.0; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1026031; Assay=Human Maximization Test; Endpoint=Relative reliability score; Response=1; Response_Unit=Unitless; Species=Human; Route=Dermal; Reference=Kligman 1966; 5924294; 10.1038/jid.1966.160|Magnusson and Kligman 1969; 5774356; 10.1038/jid.1969.42|Basketter et al. 1994; 8045461; 10.1016/0278-6915(94)90112-0|Basketter et al. 1999; 10654593; 10.1016/S0278-6915(99)00112-x|Gerberick et al. 2000; 10684384; 10.1053/ajcd.2000.0003|ICCVAM 2009; Not available; https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-ps/llnaperfstds.pdf|Basketter et al. 2014; 24407057; 10.1097/der.0000000000000003; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026031; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1026031
ECHA 8 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ECHA LOAEL >300 mg/kg bw/day Rat oral short-term; 28 days short-term QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7ca40e4b0a7c65d220eeb; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/en/registration-dossier/-/registered-dossier/14914?documentUUID=54e0385d-d8be-42fa-96a2-2833da8b378f; YEAR=1995; ORIGINAL_YEAR=1995; STUDY_GROUP=ECHA IUCLID_dup_Repeated Dose Toxicity Oral_15837311_15846939_15850935:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_65727c956caff9e29d197c65846c3964
ECHA LOAEL <=600 mg/kg bw/day Rat oral short-term; 28 days short-term QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7ca40e4b0a7c65d220eeb; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/en/registration-dossier/-/registered-dossier/14914?documentUUID=54e0385d-d8be-42fa-96a2-2833da8b378f; YEAR=1995; ORIGINAL_YEAR=1995; STUDY_GROUP=ECHA IUCLID_dup_Repeated Dose Toxicity Oral_15837311_15846939_15850935:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_4b89afeb7dd801c25b9d1d16a85710df
ECHA LOAEL =920 mg/kg bw/day Rat oral subchronic; 13 weeks subchronic QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7caabe4b0a7c65d222f7c; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/17705/7/6/2?documentUUID=40be13b0-f973-4bea-8ae5-59bb2bbb752d; YEAR=1988; ORIGINAL_YEAR=1988; STUDY_GROUP=ECHA IUCLID_dup_Repeated Dose Toxicity Oral_15837533_15839305_15850752_15850753:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_c249c79b0e2d5aa0b585ac82bf640022
ECHA NOAEL >=430 mg/kg bw/day Rat oral subchronic; 90 days subchronic QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7cb24e4b0a7c65d2250d1; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/en/registration-dossier/-/registered-dossier/14914?documentUUID=54e0385d-d8be-42fa-96a2-2833da8b378f; YEAR=1995; ORIGINAL_YEAR=1995; STUDY_GROUP=ECHA IUCLID_dup_Repeated Dose Toxicity Oral_15850519_15850520:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_a20adc29020a4eeed8dd5da8de668ffe
ECHA NOAEL =460 mg/kg bw/day Rat oral subchronic; 13 weeks subchronic QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7caabe4b0a7c65d222f7c; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/17705/7/6/2?documentUUID=40be13b0-f973-4bea-8ae5-59bb2bbb752d; YEAR=1988; ORIGINAL_YEAR=1988; STUDY_GROUP=ECHA IUCLID_dup_Repeated Dose Toxicity Oral_15837533_15839305_15850752_15850753:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_0e1a741ada86db83835715b53c57d9cb
ECHA NOAEL >=500 mg/kg bw/day Rat oral - developmental QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7d232e4b0a7c65d231fd5; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/en/registration-dossier/-/registered-dossier/14914?documentUUID=54e0385d-d8be-42fa-96a2-2833da8b378f; YEAR=1995; ORIGINAL_YEAR=1995; STUDY_GROUP=ECHA IUCLID_dup_Developmental Toxicity Teratogenicity_15824752_15824753:-:-fetal; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_7e7b0f8e685a3efcc4b0982dd6aa345e
ECHA NOAEL >600 mg/kg bw/day Rabbit oral - developmental QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7d1a6e4b0a7c65d22f953; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/17705/7/9/3?documentUUID=40be13b0-f973-4bea-8ae5-59bb2bbb752d; YEAR=1988; ORIGINAL_YEAR=1988; STUDY_GROUP=ECHA IUCLID_dup_Developmental Toxicity Teratogenicity_15824316_15824317:-:-fetal; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_7238cc689d4acc0892bdebf43f391063
ECHA NOEL =100 mg/kg bw/day Rat oral short-term; 28 days short-term QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7ca40e4b0a7c65d220eeb; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/en/registration-dossier/-/registered-dossier/14914?documentUUID=54e0385d-d8be-42fa-96a2-2833da8b378f; YEAR=1995; ORIGINAL_YEAR=1995; STUDY_GROUP=ECHA IUCLID_dup_Repeated Dose Toxicity Oral_15837311_15846939_15850935:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_95a46f0816f27e9ef136993e509af527
ToxValDB GESTIS DNEL 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB GESTIS DNEL DNEL systemic =285 mg/m3 Human inhalation - Toxicity Value STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6543dd69e4b045b9ff7cd87e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.dguv.de/ifa/gestis/gestis-dnel-liste/index-2.jsp; STUDY_GROUP=GESTIS DNEL:15634797:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_ee8e996e7763e566b137060d5186cf69
openFDA substances 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier 368GB5141J UNII - - - chemical -