Good Surfactant NOAEL Data

Sodium Myristoyl Sarcosinate

INCI: SODIUM MYRISTOYL SARCOSINATE

CAS Number
30364-51-3
Function
Mild anionic surfactant, hair conditioning, foaming agent, antistatic
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes CIR 2016 amended - safe when formulated to be non-irritating

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

3 study endpoints found for Sodium Myristoyl Sarcosinate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL >=2 other oral rat oral REACH
LOAEL 100 mg/kg bw/day oral rat oral REACH
NOAEL >=2 other oral - oral REACH

Expert Verdict

Safe mild anionic surfactant for general use. Severe ocular irritant at 20% - avoid eye-area products. Formulations must not contain nitrosating agents to prevent N-nitrososarcosine formation.

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Concern Level: Moderate

Regulatory Flags

epa_safer_alternative

Frequently Asked Questions

Is Sodium Myristoyl Sarcosinate safe in cosmetics?

Safe mild anionic surfactant for general use. Severe ocular irritant at 20% - avoid eye-area products. Formulations must not contain nitrosating agents to prevent N-nitrososarcosine formation. The EU classifies Sodium Myristoyl Sarcosinate as "permitted". Safety rating: GOOD. 3 toxicological study endpoint(s) are available in our database.

Is Sodium Myristoyl Sarcosinate allowed in the EU?

Sodium Myristoyl Sarcosinate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Sodium Myristoyl Sarcosinate do in cosmetics?

Sodium Myristoyl Sarcosinate functions as: Mild anionic surfactant, hair conditioning, foaming agent, antistatic. It is classified as a Surfactant in our database. CAS number: 30364-51-3.

What is the Margin of Safety for Sodium Myristoyl Sarcosinate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Sodium Myristoyl Sarcosinate?

The NOAEL (No Observed Adverse Effect Level) for Sodium Myristoyl Sarcosinate is >=2 other based on a oral study via oral route in rat. A total of 3 study endpoints are available. Source: REACH.

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