Good Cosmetic Ingredient NOAEL Data

Sodium PPG-16/PEG-2 Lauryl Ether Sulfate

INCI: SODIUM PPG-16/PEG-2 LAURYL ETHER SULFATE

CAS Number
68891-38-3
Function
Surfactant — cleansing, emulsifying; provides rich lather in shampoos, body washes, facial cleansers
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted in cosmetics; no specific restrictions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

7 study endpoints found for Sodium PPG-16/PEG-2 Lauryl Ether Sulfate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOEL 2.38 other dermal code:3543 dermal REACH
NOAEL >225 mg/kg bw/day oral rat oral REACH
NOAEL 0.15 other oral rat oral REACH
NOEL 3 other dermal code:3484 dermal REACH
NOEL >=1 other oral rat oral REACH
NOAEL >250 mg/kg bw/day oral - oral REACH
NOEL >250 mg/kg bw/day oral - oral REACH

Expert Verdict

PEG/PPG derivative — must test for 1,4-dioxane and ethylene oxide residuals per standard impurity protocols; ensure supplier COA includes these tests

⚠️
Concern Level: Low

Regulatory Flags

peg-ingredient epa_safer_alternative

Frequently Asked Questions

Is Sodium PPG-16/PEG-2 Lauryl Ether Sulfate safe in cosmetics?

PEG/PPG derivative — must test for 1,4-dioxane and ethylene oxide residuals per standard impurity protocols; ensure supplier COA includes these tests The EU classifies Sodium PPG-16/PEG-2 Lauryl Ether Sulfate as "permitted". Safety rating: GOOD. 7 toxicological study endpoint(s) are available in our database.

Is Sodium PPG-16/PEG-2 Lauryl Ether Sulfate allowed in the EU?

Sodium PPG-16/PEG-2 Lauryl Ether Sulfate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Sodium PPG-16/PEG-2 Lauryl Ether Sulfate do in cosmetics?

Sodium PPG-16/PEG-2 Lauryl Ether Sulfate functions as: Surfactant — cleansing, emulsifying; provides rich lather in shampoos, body washes, facial cleansers. It is classified as a cosmetic ingredient in our database. CAS number: 68891-38-3.

What is the Margin of Safety for Sodium PPG-16/PEG-2 Lauryl Ether Sulfate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Sodium PPG-16/PEG-2 Lauryl Ether Sulfate?

The NOAEL (No Observed Adverse Effect Level) for Sodium PPG-16/PEG-2 Lauryl Ether Sulfate is 2.38 other based on a dermal study via dermal route in code:3543. A total of 7 study endpoints are available. Source: REACH.

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