Good Cosmetic Ingredient NOAEL Data

Sodium Silicoaluminate

INCI: SODIUM SILICOALUMINATE

CAS Number
1344-00-9
Function
Absorbent, Anticaking, Bulking, Opacifying
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted; also GRAS as indirect food additive (21 CFR); CIR concluded safe as used

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

10 study endpoints found for Sodium Silicoaluminate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 1600 mg/kg bw/day oral mouse Developmental COSMOS_DB
NOAEL 1600 mg/kg bw/day oral rat Developmental COSMOS_DB
NOAEL 1600 mg/kg bw/day oral hamster Developmental COSMOS_DB
NOAEL 1600 mg/kg bw/day oral rabbit Developmental COSMOS_DB
dose_tested 1600 mg/kg bw/day oral mouse Developmental COSMOS_DB
dose_tested 1600 mg/kg bw/day oral rat Developmental COSMOS_DB
dose_tested 1600 mg/kg bw/day oral hamster Developmental COSMOS_DB
dose_tested 1600 mg/kg bw/day oral rabbit Developmental COSMOS_DB
NOAEL >=21.97 2104 1992 rat inhalation REACH
NOAEL >=1000 mg/kg bw/day oral rat oral REACH

Expert Verdict

Inhalation concern only โ€” respirable dust must be controlled during manufacturing (not a finished-product consumer risk); CIR notes naturally-sourced (mined) silicates require additional data for safety confirmation vs. synthetic

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Concern Level: Low

Regulatory Flags

natural-origin fda_food_additive

Frequently Asked Questions

Is Sodium Silicoaluminate safe in cosmetics?

Inhalation concern only โ€” respirable dust must be controlled during manufacturing (not a finished-product consumer risk); CIR notes naturally-sourced (mined) silicates require additional data for safety confirmation vs. synthetic The EU classifies Sodium Silicoaluminate as "permitted". Safety rating: GOOD. 10 toxicological study endpoint(s) are available in our database.

Is Sodium Silicoaluminate allowed in the EU?

Sodium Silicoaluminate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Sodium Silicoaluminate do in cosmetics?

Sodium Silicoaluminate functions as: Absorbent, Anticaking, Bulking, Opacifying. It is classified as a cosmetic ingredient in our database. CAS number: 1344-00-9.

What is the Margin of Safety for Sodium Silicoaluminate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Sodium Silicoaluminate?

The NOAEL (No Observed Adverse Effect Level) for Sodium Silicoaluminate is 1600 mg/kg bw/day based on a Developmental study via oral route in mouse. A total of 10 study endpoints are available. Source: COSMOS_DB.

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