Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
10 study endpoints found for Sorbitan Sesquicaprylate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOEL | 39.24 mg/kg bw/day | dermal | code:3484 | dermal | REACH |
| NOAEL | >=5000 mg/kg bw/day | oral | rat | oral | REACH |
| LOAEL | 5 other | oral | rat | oral | REACH |
| NOAEL | 5 other | oral | rat | oral | REACH |
| NOAEL | 5 other | oral | rat | oral | REACH |
| NOAEL | 2300 other | oral | rat | oral | REACH |
| LOAEL | 15 other | oral | rat | oral | REACH |
| LOAEL | 25 other | oral | rat | oral | REACH |
| LOAEL | 25 other | oral | rat | oral | REACH |
| NOAEL | 5 other | oral | rat | oral | REACH |
Expert Verdict
Added to CIR review in 2014 as previously unreviewed. Genotoxicity negative (Ames test). Limited standalone data but supported by extensive class data
Frequently Asked Questions
Is Sorbitan Sesquicaprylate safe in cosmetics?
Added to CIR review in 2014 as previously unreviewed. Genotoxicity negative (Ames test). Limited standalone data but supported by extensive class data The EU classifies Sorbitan Sesquicaprylate as "permitted". Safety rating: GOOD. 10 toxicological study endpoint(s) are available in our database.
Is Sorbitan Sesquicaprylate allowed in the EU?
Sorbitan Sesquicaprylate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Sorbitan Sesquicaprylate do in cosmetics?
Sorbitan Sesquicaprylate functions as: Surfactant – Emulsifying Agent (mixture of mono- and diesters of caprylic acid and hexitol anhydrides). It is classified as a cosmetic ingredient in our database. CAS number: 91844-53-0.
What is the Margin of Safety for Sorbitan Sesquicaprylate?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Sorbitan Sesquicaprylate?
The NOAEL (No Observed Adverse Effect Level) for Sorbitan Sesquicaprylate is 39.24 mg/kg bw/day based on a dermal study via dermal route in code:3484. A total of 10 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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