Good Cosmetic Ingredient Sensitization Data

Stearamidopropyl Dimethylamine

INCI: STEARAMIDOPROPYL DIMETHYLAMINE

CAS Number
7651-02-7
Function
Antistatic, Emulsifying, Hair Conditioning, Surfactant
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes CIR reviewed (2014) โ€” safe when formulated to be non-sensitizing

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Sensitization Profile

Contact sensitization data for Stearamidopropyl Dimethylamine based on clinical patch test studies and IFRA standards.

Sensitization Rate
low
Allergen Class
surfactant
EU Allergen Listed
no
Patch Test Positive Rate
0.3%
Cross-reactivity Group
amidoamine-group
Reaction Type
contact-dermatitis

Source: NACDG; IVDK; ESSCA

Expert Verdict

Most-used ingredient in this amidopropyl dimethylamine class; DMAPA and amidoamine impurities are the primary sensitization risk; must perform QRA to confirm non-sensitizing formulation; cationic surfactant replacement for silicones in hair care

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Concern Level: Moderate

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Stearamidopropyl Dimethylamine safe in cosmetics?

Most-used ingredient in this amidopropyl dimethylamine class; DMAPA and amidoamine impurities are the primary sensitization risk; must perform QRA to confirm non-sensitizing formulation; cationic surfactant replacement for silicones in hair care The EU classifies Stearamidopropyl Dimethylamine as "permitted". Safety rating: GOOD.

Is Stearamidopropyl Dimethylamine allowed in the EU?

Stearamidopropyl Dimethylamine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Stearamidopropyl Dimethylamine do in cosmetics?

Stearamidopropyl Dimethylamine functions as: Antistatic, Emulsifying, Hair Conditioning, Surfactant. It is classified as a cosmetic ingredient in our database. CAS number: 7651-02-7.

What is the Margin of Safety for Stearamidopropyl Dimethylamine?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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