Stearyldisulfidehexyl SH-DNA-2 PEG-45/SH-RNA-1

INCI: STEARYLDISULFIDEHEXYL SH-DNA-2 PEG-45/SH-RNA-1

CAS Number
Not assigned (biotech conjugate)
Function
Hair conditioning (PEG-conjugated nucleic acid delivery system)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No specific restriction; novel biotech ingredient โ€” may require additional scrutiny under MoCRA

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Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

๐Ÿ”ด Novel biotech ingredient โ€” no CIR review, no SCCS opinion, no published toxicological dossier. Contains nucleic acid fragments (DNA/RNA) โ€” regulatory scrutiny increasing for this class. Ethylene oxide residuals possible from PEG-45 โ€” test for EO/1,4-dioxane. Disulfide bond may release thiol fragments on skin

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Concern Level: High

Regulatory Flags

peg-ingredient

Frequently Asked Questions

Is Stearyldisulfidehexyl SH-DNA-2 PEG-45/SH-RNA-1 safe in cosmetics?

๐Ÿ”ด Novel biotech ingredient โ€” no CIR review, no SCCS opinion, no published toxicological dossier. Contains nucleic acid fragments (DNA/RNA) โ€” regulatory scrutiny increasing for this class. Ethylene oxide residuals possible from PEG-45 โ€” test for EO/1,4-dioxane. Disulfide bond may release thiol fragments on skin The EU classifies Stearyldisulfidehexyl SH-DNA-2 PEG-45/SH-RNA-1 as "permitted". Safety rating: MODERATE.

Is Stearyldisulfidehexyl SH-DNA-2 PEG-45/SH-RNA-1 allowed in the EU?

Stearyldisulfidehexyl SH-DNA-2 PEG-45/SH-RNA-1 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Stearyldisulfidehexyl SH-DNA-2 PEG-45/SH-RNA-1 do in cosmetics?

Stearyldisulfidehexyl SH-DNA-2 PEG-45/SH-RNA-1 functions as: Hair conditioning (PEG-conjugated nucleic acid delivery system). It is classified as a cosmetic ingredient in our database. CAS number: Not assigned (biotech conjugate).

What is the Margin of Safety for Stearyldisulfidehexyl SH-DNA-2 PEG-45/SH-RNA-1?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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