Moderate Cosmetic Ingredient NOAEL Data

Tallowdimonium Propyltrimonium Dichloride

INCI: TALLOWDIMONIUM PROPYLTRIMONIUM DICHLORIDE

CAS Number
68607-29-4
Function
Antistatic agent, hair conditioning agent, surfactant
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted for cosmetic use; no specific restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

3 study endpoints found for Tallowdimonium Propyltrimonium Dichloride. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL ca.10 mg/kg bw/day oral rat oral REACH
NOAEL 80 mg/kg bw/day oral rat oral REACH
NOAEL ca.10 mg/kg bw/day oral rat oral REACH

Expert Verdict

BSE/TSE prion risk (tallow-derived); potential skin/eye irritation at higher concentrations; chloride counterion is standard

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Concern Level: Moderate

Frequently Asked Questions

Is Tallowdimonium Propyltrimonium Dichloride safe in cosmetics?

BSE/TSE prion risk (tallow-derived); potential skin/eye irritation at higher concentrations; chloride counterion is standard The EU classifies Tallowdimonium Propyltrimonium Dichloride as "permitted". Safety rating: MODERATE. 3 toxicological study endpoint(s) are available in our database.

Is Tallowdimonium Propyltrimonium Dichloride allowed in the EU?

Tallowdimonium Propyltrimonium Dichloride EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Tallowdimonium Propyltrimonium Dichloride do in cosmetics?

Tallowdimonium Propyltrimonium Dichloride functions as: Antistatic agent, hair conditioning agent, surfactant. It is classified as a cosmetic ingredient in our database. CAS number: 68607-29-4.

What is the Margin of Safety for Tallowdimonium Propyltrimonium Dichloride?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Tallowdimonium Propyltrimonium Dichloride?

The NOAEL (No Observed Adverse Effect Level) for Tallowdimonium Propyltrimonium Dichloride is ca.10 mg/kg bw/day based on a oral study via oral route in rat. A total of 3 study endpoints are available. Source: REACH.

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