NOAEL Studies Cosmetic Ingredient

Tetramethylammonium Chloride NOAEL Studies

INCI: TETRAMETHYLAMMONIUM CHLORIDE

CAS: 75-57-0

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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ToxValDB_ECHA_IUCLID 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_ECHA_IUCLID NOAEL =10 mg/kg bw/day Rat oral subchronic; 90 days subchronic QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eaee3e4b0a7c65d1cb83c; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/19457/7/6/2?documentUUID=138d9ade-879d-4def-8331-d99aafef0382; YEAR=2013; ORIGINAL_YEAR=2013; TOXICOLOGICAL_EFFECT=liver: histopathology: non-neoplastic|organ weights and organ / body weight ratios; TOXICOLOGICAL_EFFECT_CATEGORY=nonneoplastic histopathology|organ weight; STUDY_GROUP=ECHA IUCLID_dup_Repeated Dose Toxicity Oral_15839089_15845365:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_c2bbfe0909349dca646e9e74d76fc582
ToxValDB_GESTIS_DNEL 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_GESTIS_DNEL DNEL systemic =2.9 mg/m3 Human inhalation - Toxicity Value STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6543dd69e4b045b9ff7cd87e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.dguv.de/ifa/gestis/gestis-dnel-liste/index-2.jsp; STUDY_GROUP=GESTIS DNEL:15635153:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_71b53d725815ba7ee388b42a4a4ce5a7
openFDA substances 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier DCQ9S88703 UNII - - - chemical {"approval_status":null,"molecular_formula":"C4H12N.Cl","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"DCQ9S88703"}
openFDA substances FDA UNII substance identifier DCQ9S88703 UNII - - - chemical {"approval_status":null,"molecular_formula":"C4H12N.Cl","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"DCQ9S88703"}
openFDA substances FDA UNII substance identifier DCQ9S88703 UNII - - - chemical {"approval_status":null,"molecular_formula":"C4H12N.Cl","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"DCQ9S88703"}
openFDA substances FDA UNII substance identifier DCQ9S88703 UNII - - - chemical {"approval_status":null,"molecular_formula":"C4H12N.Cl","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"DCQ9S88703"}