Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Considered safe at cosmetic-use levels with no significant safety concerns.
Frequently Asked Questions
Is Tetrapeptide-5 safe in cosmetics?
Considered safe at cosmetic-use levels with no significant safety concerns. The EU classifies Tetrapeptide-5 as "permitted". Safety rating: GOOD.
Is Tetrapeptide-5 allowed in the EU?
Tetrapeptide-5 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Tetrapeptide-5 do in cosmetics?
Tetrapeptide-5 functions as: Humectant, moisturizing, soothing, smoothing, refreshing; anti-puffiness agent; inhibits glycosylation; increases SOD activity. It is classified as a cosmetic ingredient in our database. CAS number: 883220-97-1 (Tetrapeptide-5); 820959-17-9 (Acetyl Tetrapeptide-5).
What is the Margin of Safety for Tetrapeptide-5?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
Check Tetrapeptide-5 compliance across multiple jurisdictions:
Related Ingredients
Is Tetrapeptide-5 in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Tetrapeptide-5 in your formulation.