Good Cosmetic Ingredient NOAEL Data

Theobroma Cacao Shell Extract

INCI: THEOBROMA CACAO SHELL EXTRACT

CAS Number
84649-99-0
Function
Antioxidant, Skin Conditioning
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted for cosmetic use; no standalone CIR monograph

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

2 study endpoints found for Theobroma Cacao Shell Extract. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 4280 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB
NOAEL 2140 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB

Expert Verdict

Cacao shells may concentrate heavy metals (cadmium, lead) from soil โ€” verify supplier CoA for heavy metal content per EU 1223/2009 impurity limits; extraction solvent residues must comply with EU limits

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Concern Level: Low

Regulatory Flags

plant-extract fda_food_additive

Frequently Asked Questions

Is Theobroma Cacao Shell Extract safe in cosmetics?

Cacao shells may concentrate heavy metals (cadmium, lead) from soil โ€” verify supplier CoA for heavy metal content per EU 1223/2009 impurity limits; extraction solvent residues must comply with EU limits The EU classifies Theobroma Cacao Shell Extract as "permitted". Safety rating: GOOD. 2 toxicological study endpoint(s) are available in our database.

Is Theobroma Cacao Shell Extract allowed in the EU?

Theobroma Cacao Shell Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Theobroma Cacao Shell Extract do in cosmetics?

Theobroma Cacao Shell Extract functions as: Antioxidant, Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 84649-99-0.

What is the Margin of Safety for Theobroma Cacao Shell Extract?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Theobroma Cacao Shell Extract?

The NOAEL (No Observed Adverse Effect Level) for Theobroma Cacao Shell Extract is 4280 mg/kg bw/day based on a Short Term Toxicity study via oral route in rat. A total of 2 study endpoints are available. Source: COSMOS_DB.

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